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Kumbhar, Arjun
- Green Protocol for the Synthesis of 1,8-Dioxo-Decahydroacridines by Hantzsch Condensation Using Citric Acid as Organocatalyst
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Authors
Monika Patil
1,
Shrikrishna Karhale
1,
Ananada Kudale
1,
Arjun Kumbhar
2,
Sagar More
2,
Vasant Helavi
1
Affiliations
1 Department of Chemistry, Rajaram College, Kolhapur 416 004, IN
2 Department of Chemistry, P. D. V. P. College, Tasgaon 416 312, IN
1 Department of Chemistry, Rajaram College, Kolhapur 416 004, IN
2 Department of Chemistry, P. D. V. P. College, Tasgaon 416 312, IN
Source
Current Science, Vol 116, No 6 (2019), Pagination: 936-942Abstract
Herein we describe a clean and sustainable, one-pot, multi-component protocol for the synthesis of 1,8- dioxo-decahydroacridines by Hantzsch condensation of cyclic 1,3-dicarbonyl compound and NH4OAc with diverse aryl aldehydes using citric acid as an inexpensive green additive in ecological safe solvent. Utilization of cheaper and safer catalyst, cleaner reaction profile, straightforward work-up procedure and good to excellent yields of the desired product are the noteworthy aspects of this method.Keywords
Acridines, Citric Acid, Organocatalysts, Green Protocol, Multi-Component Reactions.Full Text
References
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