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Determination of oxidant and antioxidant parameters in the serum of children with type 1 diabetes mellitus


Affiliations
1 Department of Hotel, Restaurant and Catering Services, Cookery Program, Bitlis Eren University, Bitlis, Turkey., Turkey
2 Söke Health Services Vocational School, Department of Health Care Services, Home Patient Care Program, Aydın Adnan Menderes University,Aydin, Turkey., Turkey
3 Faculty of Medicine, Department of Pediatric Endocrinology, Aydın Adnan Menderes University, Aydin, Turkey., Turkey
4 Faculty of Health Sciences, Department of Nutrition and Dietetics, Aydın Adnan Menderes University, Aydin, Turkey., Turkey
 

The primary goal of this study was to assess the oxidant/ antioxidant balance of children and adolescents with type 1 diabetes mellitus (T1DM). It was an experimental case-control study with 38 children and adolescents diagnosed with T1DM. We found that the fasting blood glucose, haemoglobinA1c, malondialdehyde, total oxidant status, and total and native thiol values of the type-1 diabetes group were significantly higher than the control group, while total antioxidant status was significantly lower. Our results corroborate other studies showing diabetic patients are more vulnerable to oxidative stress.

Keywords

Adolescents, Children, Diabetes Mellitus, Oxidant and Antioxidant Parameters.
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  • Determination of oxidant and antioxidant parameters in the serum of children with type 1 diabetes mellitus

Abstract Views: 119  |  PDF Views: 77

Authors

Yakup Enes Çam
Department of Hotel, Restaurant and Catering Services, Cookery Program, Bitlis Eren University, Bitlis, Turkey., Turkey
Murat Ari
Söke Health Services Vocational School, Department of Health Care Services, Home Patient Care Program, Aydın Adnan Menderes University,Aydin, Turkey., Turkey
Ahmet Anik
Faculty of Medicine, Department of Pediatric Endocrinology, Aydın Adnan Menderes University, Aydin, Turkey., Turkey
Serdal Öğüt
Faculty of Health Sciences, Department of Nutrition and Dietetics, Aydın Adnan Menderes University, Aydin, Turkey., Turkey

Abstract


The primary goal of this study was to assess the oxidant/ antioxidant balance of children and adolescents with type 1 diabetes mellitus (T1DM). It was an experimental case-control study with 38 children and adolescents diagnosed with T1DM. We found that the fasting blood glucose, haemoglobinA1c, malondialdehyde, total oxidant status, and total and native thiol values of the type-1 diabetes group were significantly higher than the control group, while total antioxidant status was significantly lower. Our results corroborate other studies showing diabetic patients are more vulnerable to oxidative stress.

Keywords


Adolescents, Children, Diabetes Mellitus, Oxidant and Antioxidant Parameters.

References





DOI: https://doi.org/10.18520/cs%2Fv124%2Fi7%2F807-811