Current Science

Open Access Open Access  Restricted Access Subscription Access

Persistence of Chikungunya Virus in Samples Stored at Different Temperatures


Affiliations
1 ICMR-National Institute of Virology, 20A, Ambedkar Road, Pune 411 001, India
 

Chikungunya virus (CHIKV), a mosquito-borne alphavirus (family Togaviridae), has become a globally major public health problem since 2004 (ref. 1). No vaccines or therapeutics are available except for mosquito control. CHIKV is relatively stable in blood at room temperature and remains viable for at least 8 h (ref. 2). However, no documented data is available regarding survival of CHIKV outside the host, i.e. in serum or infected mosquitoes. Understanding the survival and environmental stability of CHIKV in the above samples is important for effective management during outbreaks and handling clinical samples.
User
Notifications
Font Size

  • Peterson, L. R. and Powers, A. M., Chikungunya: epidemiology. F1000Res (2016); 5. pii: F1000 Faculty Rev-82. doi:10.12688/f1000research.7171.1.eCollection 2016.

  • Ramachandrarao, T., Sharda Devi, P. and Singh, K. R., Mosq. News, 1968, 28, 406–408.

  • Sudeep, A. B., Ghodke, Y. S., Gokhale, M. D., George, R. P., Dhaigude, S. D. and Bondre, V. P., J. Vector Borne Dis., 2014, 51, 333–338.

  • Reed, L. J. and Muench, H. A., Am. J. Hyg., 1938, 27, 493–497.

  • Parashar, D., Amdekar, S., More, A., More, R., Patil, P. and Ravindra Babu, V., Indian J. Med. Res. (Supplement), 2015, 142, 62–66.

  • Parashar, D., Paingankar, M. S., Sudeep, A. B., More, A., Shinde, S. and Arankalle, V. A., Curr. Sci., 2014, 107, 211–213.

  • Parashar, D., Paingankar, M. S., Kumar, S., Gokhale, M. D., Sudeep, A. B., Shinde, S. B. and Arankalle, V. A., PLoS Negl. Trop. Dis., 2013, 7, e2405.

  • Mavale, M. et al., Am. J. Trop. Med. Hyg., 2012, 86, 178–180.

  • Damjanovic, V., J. Hosp. Infect., 1987, 10, 209–211.

  • Dimmock, N. J., Virology, 1967, 31, 338–353.

  • Salvucci, J. T., Cell Tissue Bank, 2011, 12, 99–104.

  • Bean, B., Moore, B. M., Sterner, B., Peterson, L. R., Gerding, D. N. and Balfour Jr, H. H., J. Infect. Dis., 1982, 146, 47–51.

  • Sebire, K., McGavin, K., Land, S., Middleton, T. and Birch, C., J. Clin. Microbiol., 1998, 36, 493–498.

  • Tjotta, E., Hungnes, O. and Grinde, B., J. Med. Virol., 1991, 35, 223–227.

  • Paintsil, E., Binka, M., Patel, A., Lindenbach, B. D. and Heimer, R., J. Infect. Dis., 2014, 209, 1205–1211.

  • Detmer, J. et al., J. Clin. Microbiol., 1996, 34, 901–907.


Abstract Views: 496

PDF Views: 85




  • Persistence of Chikungunya Virus in Samples Stored at Different Temperatures

Abstract Views: 496  |  PDF Views: 85

Authors

Deepti Parashar
ICMR-National Institute of Virology, 20A, Ambedkar Road, Pune 411 001, India
A. B. Sudeep
ICMR-National Institute of Virology, 20A, Ambedkar Road, Pune 411 001, India
Ashwini More
ICMR-National Institute of Virology, 20A, Ambedkar Road, Pune 411 001, India
Poonam Patil
ICMR-National Institute of Virology, 20A, Ambedkar Road, Pune 411 001, India
Atul Walimbe
ICMR-National Institute of Virology, 20A, Ambedkar Road, Pune 411 001, India
Mangala Mavale
ICMR-National Institute of Virology, 20A, Ambedkar Road, Pune 411 001, India
Sarika Amdekar
ICMR-National Institute of Virology, 20A, Ambedkar Road, Pune 411 001, India

Abstract


Chikungunya virus (CHIKV), a mosquito-borne alphavirus (family Togaviridae), has become a globally major public health problem since 2004 (ref. 1). No vaccines or therapeutics are available except for mosquito control. CHIKV is relatively stable in blood at room temperature and remains viable for at least 8 h (ref. 2). However, no documented data is available regarding survival of CHIKV outside the host, i.e. in serum or infected mosquitoes. Understanding the survival and environmental stability of CHIKV in the above samples is important for effective management during outbreaks and handling clinical samples.

References





DOI: https://doi.org/10.18520/cs%2Fv115%2Fi1%2F25-27