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Wound Healing Materials - A Perspective for Skin Tissue Engineering


Affiliations
1 School of Bio Sciences and Technology, VIT University, Vellore 632 014, India
2 Department of Manufacturing, School of Mechanical Engineering, VIT University, Vellore 632 014, India
 

Skin injury and wound healing are complex biological and intricate processes that involve activation of intercellular pathways, co-ordination of tissue integrity and homeostasis. The wound can be acute and chronic depending upon the nature and depth of the injury. A wide variety of dressing materials is available to enhance the wound healing process. An ideal dressing should act as a three-dimensional template which can mimic extracellular matrix, be biologically stable, flexible and can remove wound exudate by providing a moist environment to the wound site. It should form a protective bed to cover the wound from external hazards. This article presents a review of wound dressings made of natural and synthetic polymers or a combination of both. A variety of commercial wound healing materials is discussed briefly.

Keywords

Extra Cellular Matrix, Polymer Dressings, Skin Injury, Wound Healing.
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  • Wound Healing Materials - A Perspective for Skin Tissue Engineering

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Authors

Poulami Basu
School of Bio Sciences and Technology, VIT University, Vellore 632 014, India
U. Narendra Kumar
Department of Manufacturing, School of Mechanical Engineering, VIT University, Vellore 632 014, India
I. Manjubala
School of Bio Sciences and Technology, VIT University, Vellore 632 014, India

Abstract


Skin injury and wound healing are complex biological and intricate processes that involve activation of intercellular pathways, co-ordination of tissue integrity and homeostasis. The wound can be acute and chronic depending upon the nature and depth of the injury. A wide variety of dressing materials is available to enhance the wound healing process. An ideal dressing should act as a three-dimensional template which can mimic extracellular matrix, be biologically stable, flexible and can remove wound exudate by providing a moist environment to the wound site. It should form a protective bed to cover the wound from external hazards. This article presents a review of wound dressings made of natural and synthetic polymers or a combination of both. A variety of commercial wound healing materials is discussed briefly.

Keywords


Extra Cellular Matrix, Polymer Dressings, Skin Injury, Wound Healing.

References





DOI: https://doi.org/10.18520/cs%2Fv112%2Fi12%2F2392-2404