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Roy, Amit
- Importance and Utility of Vagina as a Route for Drug Delivery System
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Authors
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1 Columbia Institute of Pharmacy, Tekari, Raipur, IN
1 Columbia Institute of Pharmacy, Tekari, Raipur, IN
Source
Asian Journal of Research in Pharmaceutical Sciences, Vol 4, No 2 (2014), Pagination: 86-92Abstract
The purpose of this review article is to highlight the importance of vaginal drug delivery system. Several studies proven that vagina is an effective route for drug administration intended for local action as well as systemic action. This route offers many advantages due to its large permeation area, permeability to large molecular weight drugs, rich vascularization, avoidance of first pass metabolism and relatively low enzymatic activity. Through this route steroidal compounds, spermicidal agents are already delivered to obtain suitable therapeutics action for prolong period of time with minimal side effects. Recently the vaginal route has been investigated for peptide and protein drug delivery. In this review we focused on different aspects related to vaginal drug delivery systems along with their anatomy physiology and factors affecting drug absorption from the vaginal route.Keywords
Vagina, Intravaginal Route, Peptide and Protein Drug Delivery.References
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- Phytochemical Screening and Antioxidant Activity of Sesbania grandiflora Leaves Extracts
Abstract Views :239 |
PDF Views:2
Authors
Affiliations
1 Columbia Institute of Pharmacy, Tekari, Raipur (C.G.), IN
2 Oriental College of Pharmacy, Raisen Road, Bhopal (M.P.), IN
3 Department of Chemistry, Banasthali University, Rajasthan, IN
1 Columbia Institute of Pharmacy, Tekari, Raipur (C.G.), IN
2 Oriental College of Pharmacy, Raisen Road, Bhopal (M.P.), IN
3 Department of Chemistry, Banasthali University, Rajasthan, IN
Source
Asian Journal of Research in Pharmaceutical Sciences, Vol 4, No 1 (2014), Pagination: 16-21Abstract
Sesbania grandiflora, family: Fabaceae commonly known as 'sesbania', is widely used as Indian folk medicine. S.grandiflora has the common names of Agati, Corkwood Tree and West Indian Pea. In India it is known as vaka or basna. Traditionally Sesbania grandiflora, is used alone or with other medicinal plants to treat a variety of ailments. The plant's extracts were screened for the presence of phytochemicals and were used to determine their free radical scavenging activity. The extracts showed potent antioxidant activity in the scavenging of DPPH radicals. The potent antioxidant activity of the ethanolic and aqueous extracts of Sesbania grandiflora, may be due to the high phenolic content such as tannins and flavonoids, was proved by estimation of total phenolic content.Keywords
Sesbania grandiflora, Phytochemical Screening, Phenolic Content, Antioxidant Activity.References
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