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Kharkhanis, Vaishali V.
- Development and Validation of UV Spectrophotometric method for estimation of Ethamsylate in bulk and pharmaceutical dosage forms
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Authors
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1 A.R. College of Pharmacy and G.H. Patel Institute of Pharmacy, Vallabh Vidhyanagar, Dist: Anand, Gujarat
1 A.R. College of Pharmacy and G.H. Patel Institute of Pharmacy, Vallabh Vidhyanagar, Dist: Anand, Gujarat
Source
Asian Journal of Research in Chemistry, Vol 6, No 2 (2013), Pagination: 166-168Abstract
A selective, simple, accurate and reproducible spectrophotometric method has been developed for the estimation of Ethamsylate in bulk and pharmaceutical formulation. The drug obeyed the Beer's law and showed good correlation. It showed absorption maxima at 300nm in 0.1N HCL. The developed method was validated with respect to linearity, accuracy and precision. The linearity was observed between 10-35μg/ml having line equationY=0.018x-0.0098with correlation coefficient of 0.999. Results of the analysis were validated statistically and by recovery studyKeywords
UV-Vis Spectrophotometer, Ethamsylate, Recovery, maxReferences
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