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Authors
Affiliations
1 Nadkarny-Sacasa Research Laboratory, Department of Chemistry, St. Xavier’s College, Mumbai - 400 001, IN
Source
Asian Journal of Research in Chemistry, Vol 4, No 12 (2011), Pagination: 1840-1843
Abstract
The acid hydrazides (I and IV) were condensed with indole-2,3-dione in ethanol to yield hydrazono-indolin-2-ones (II and V) which on aminomethylation with formaldehyde and different amines furnished 1-(substituted aminomethyl)-hydrazono-indolin-2-ones (IIIa-e and VIa-e). The structures of the newly synthesized compounds have been confirmed by IR, 1H NMR and Mass spectra. These compounds have shown promising biological activity.
Keywords
Synthesis, Mannich Bases, Biological Activity and Spectral Data.