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Authors
Affiliations
1 Tallapadmavathi College of Pharmacy, Urus, Kareemabad, Warangal, A.P, IN
2 Trinity College of Pharmaceutical Sciences, Peddapalli, Karimnagar, A.P, IN
3 Balaji Institute of Pharmaceutical Sciences, Narsampet, Warangal, A.P, IN
Source
Asian Journal of Research in Chemistry, Vol 4, No 1 (2011), Pagination: 147-150
Abstract
Seven different 2-[(1H-benzimidazol-2yl methyl) sulfanyl)] –N4-(phenylmethylidene) acetohydrazides were synthesized from 2-[(1H- benzimidazol-2-yl methyl) sulfanyl] acetohydrazide on reaction with different aromatic aldehydes in methanol. Each of these compounds were purified and characterized by their spectral data. All the compounds were assayed for their anti-inflammatory activity by carrageenan induced rat hind paw edema method. Some of these compounds showed moderate to considerable anti-inflammatory activity.
Keywords
Benzimidazol-2-methane Thiol Derivatives, Aromatic Aldehydes, Anti-Inflammatory Activity.
