Asian Journal of Research in Chemistry

B. R. Thorat ¹, M. Mustapha ¹, Dyaneshwar Shelke ¹, Ram Jadhav ¹, Swati Lele ¹, R. G. Atram ², R. Yamgar ¹

Affiliations
1 P. G. Dept of Chemistry, Govt. of Maharashtra, Ismail Yusuf College of Arts, Science and Commerce, Jogeshwari (East), Mumbai 400 060, IN
2 Dept of Chemistry, Govt. of Maharashtra, Ismail Yusuf College of Arts, Science and Commerce, Jogeshwari (East), Mumbai 400 060, IN

Abstract

Schiff bases are versatile ligands which are synthesized by the condensation of primary amines with carbonyl groups of aldehydes or ketones. The fluorescence intensity can be increased by the formation of metal complex. Anthranilic acid or 2-aminophenol reacts with aldehydes or ketones forming bidentate or tridentate ligands which are able to form complex with transition metals. These ligands/chelates forming complexes with Zn(II) and Cu(II) metal ions. The Zn(II) complexes are yellow in nature while Cu(II) light blue color shows absorption in UV region.

Keywords

Schiff Bases, Anthranilic Acid, 2-Hydroaniline, Aldehydes, Fluorescence, Complexes.

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Ashok G. Gadre ¹, V. V. Nawathye ¹, D. B. Dalavi ¹, D. J. Upadhyaya ¹, B. R. Thorat ¹, R. S. Yamgar ¹

Affiliations
1 Chemistry Research Laboratory, Patkar-Varde College, Goregaon (W), Mumbai 62, IN

Abstract

8-Amino-6-chlorocoumarine has been synthesized by multistep synthesis which involves the successive chlorination and nitration of salicylaldehyde. The coumarin was synthesized by using Perkin reaction. The resulting nitrocompound can be reduced to 8-amino-6-chlorocoumarine. This was then diazotized and then coupled with different β-diketones and β-ketoesters gives corresponding hydrazones. The hydrazones were cyclized by reacting with hydrazines to get pyrazole and pyrazolone derivatives.

Keywords

Coumarin, Hydrazones, Pyrazoles, Pyrazolones, Hydrazines, β-Biketones.

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Vijaya Pawar ¹, Sangeeta V. Chavan ¹, Ramesh S. Yamgar ¹, R. G. Atram ², B. R. Thorat ², Swati Bisht ², Sudhir S. Sawant ²

Affiliations
1 Department of Chemistry, Patkar College of Arts and Science, Goregaon (W), Mumbai 400 062, IN
2 P. G. Dept of Chemistry, Govt. of Maharashtra’s Ismail Yusuf College of Arts, Science and Commerce, Jogeshwari (East), Mumbai 400 060, IN

Abstract

Novel transition metal Cu(II), Ni(II), Co(II) and Zn(II) ions complexes of bidentate Schiff base ligand obtained from 4-Methyl 7-hydroxy 8-formyl coumarin, and Dimethylamino propylene diamine have been prepared and characterized by physical, spectral and analytical data. The synthesized Schiff base act as bidentate ligand for the complexation reaction with Cu(II), Ni(II), Co(II) and Zn(II) ions. The new compounds, possessing the general formula [M(L)₂.2H₂O] where [M= Cu(II), Ni(II), Co(II) and Zn(II)] show octahedral geometry. In order to evaluate the effect of metal ions upon chelation, the Schiff base and their metal complexes have been screened for antimicrobial activity. The transition metal complexes have shown enhanced antimicrobial activities as compared to Schiff base.

Keywords

Schiff Bases, 4-Methyl 7-Hydroxy 8-Formyl Coumarin, Transition Metal Complexes.

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