Asian Journal of Research in Chemistry

A. Jamal Abdul Nasser ¹, A. Pasupathy ², R. Surendra Kumar ¹, A. Idhayadhulla ¹

Affiliations
1 P.G. and Research Dept. of Chemistry, Jamal Mohamed College, Tiruchirappalli-620020, Tamil Nadu, IN
2 Department of Chemistry, Urumu Dhanalakshmi College, Tiruchirappalli-620019, Tamil Nadu, IN

Abstract

2,6-dipheyl-piperidin-4-thiosemicarbazone (DPPTSC) ligand and their metal (Co^II, Ni^II, Cu^II, Cd^II) complexes have been synthesized and characterized by IR, ¹H NMR, elemental analysis, molar conductance, magnetic susceptibility measurements. The electrochemical property was studied by cyclic voltammeter. All the metal complexes are [ML₂Cl₂] type, where M= Co, Ni Cu, Cd and L=DPPTSC act as a bidentate ligand in all the complexes. Distorted octahedral geometry for Cu complex and octahedral geometries for all other complexes are proposed. The newly synthesized metal complexes have been screened at in vitro for their antimicrobial activity against five bacterial strains and five fungai strains, all the complexes and ligand CPPTSC possess strong inhibitory action against bacteria and fungi, the antimicrobial activities of the complexes are stronger than those of ligand CPPTSC itself.

Keywords

2, 6-Diphenyl-Piperidin-4-Thiosemicarbazone, Transition Metal (II) Complexes, Spectral Study, Electrochemical Behavior, Antibacterial Activity.

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