Asian Journal of Pharmacy and Technology

P. Jaya Preethi ¹, E. Karthikeyan ¹, M. Lohita ¹, P. Goutham Teja ¹, M. Subhash ¹, P. Shaheena ¹, Y. Prashanth ¹, K. Sai Nandhu ¹

Affiliations
1 Department of Pharmacy, Sree Vidyanikethan College of Pharmacy, Tirupati, IN

Abstract

Benzimidazole is the heterocyclic compound formed by the fusion of benzene and imidazole ring. Benzimidazole derivatives belong to a crucial structural design that is seen in many pharmaceutically and biologically interesting molecules. Benzimidazole has shown potential for application in a variety of pharmacological targets. They have been intensively used in medicinal chemistry as drugs such as antihistaminic, antiulcerative, antihelmentic, antipsychotic etc. Benzimidazole is outstandingly effective compounds and there are a number of reviews available for biochemical and pharmacological studies which confirmed that these molecules are useful against a wide variety of microorganisms. For these reasons, they achieved much attention as important pharmacophore and privileged structure in medicinal chemistry. This review summarizes to know about the different derivatives of Benzimidazole.

Keywords

Pharmacological Activities, Substituted Benzimidazole, Benzimidazole Derivatives.

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P. Jaya Preethi ¹, W. Shinto Authur ¹, M. Lohita ¹, K. Swetha ¹, D. Naresh ¹

Affiliations
1 Department of Pharmacy, Sree Vidyanikethan College of Pharmacy, Sri Sainath nagar, Tirupati-517102, IN

Abstract

Plants have been the beacon of therapeutic sources for curing diseases from times immemorial. We emphasize the role of information derived from various systems of traditional medicine (ethnomedicine) and its utility for drug discovery purposes. Cancer is a dreadful disease characterized by the irregular proliferation of the cells. As a cell progresses from normal to cancerous, the biological imperative to survive and perpetuate drives fundamental changes in cell behaviour. An attempt has been made to review some medicinal plants used for the prevention and treatment of cancer.

Keywords

Anticancer, Medicinal Plants, Herbal Medicine, Cancer Treatment, Curcuma Longa, Azadirachata Indica.

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