Asian Journal of Pharmacy and Technology

Hemlata Bhawar ¹, Nachiket Dighe ¹, Pankaj Shinde ¹, Ravi Lawre ², Sanjay Bhawar ³

Affiliations
1 Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni-413736, MS, IN
2 Department of Quality Assurance Technique, Pravara Rural College of Pharmacy, Loni-413736, MS, IN
3 Department of Pharmacology, Pravara Rural College of Pharmacy, Loni-413736, MS, IN

Abstract

The synthesis, structure and biological activity of Imidazole derivatives have long been the focus of research interests in the field of Medicinal Chemistry. A number of Imidazole derivatives have been reported to possess interesting biological activities such as Antimicrobial, Anti-inflammatory and Antifungal activities etc. Around 22 new derivatives were synthesized, with the standard chemicals and well established procedures. The synthesized compounds were tested for their preliminary tests, physical constants, TLC etc. IR, 1H-NMR Spectra and CHN analysis confirmed the structures of the final compounds. The proposed compounds were screened for their antimicrobial and anti-inflammatory activities with the standard drugs in the well-equipped microbiology and pharmacology lab by using standard methods.

Keywords

Anti-Inflammatory, Antimicrobial and Imidazole.

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