Asian Journal of Pharmacy and Technology

D. M. Shinkar ¹, D. B. Pandya ², R. B. Saudagar ²

Affiliations
1 Department of Pharmaceutics, KCT’s R.G.S. College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra
2 Department of Pharmaceutics, KCT’s R.G.S. College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, IN

Abstract

Kleptomania is an impulse control disorder characterised by emotional or behavioural self-control. Patient fails to resist impulses to steal items although not required for personal use or for monetary value. The symptoms include repeated theft of objects not needed, increasing tension before committing theft and relief after theft. The present article gives account on causes of disorder, its symptoms, history, different approaches to treat disorder and various hormonal imbalance associated with it. Various antidepressant drugs have been in use for the treatment along with psychotherapy.

Keywords

Kleptomania, Impulse Control Disorder, Selective Serotonin Reuptake Inhibitors.

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D. M. Shinkar ¹, A. N. Patil ¹, R. B. Saudagar ²

Affiliations
1 Department of Pharmaceutics, R.G. Sapkal college of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, IN
2 Department of Pharmaceutical Chemistry, R.G. Sapkal college of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, IN

Abstract

Enhancement of solubility, dissolution rate and bioavailability of drug is a very challenging task in drug development, nearly 40% of the new chemical entities currently being discovered are poorly water soluble drugs. The solubility behavior of the drugs remain one of the most challenging aspects in formulation development. This results in important products not reaching the market or not achieving their full potential. Solid dispersion is one of the techniques adopted for the formulation of such drugs and various methods are used for the preparation of solid dispersion. Solid dispersion is generally prepared with drug which is having poor aqueous solubility and hydrophilic carrier. This article review various methods and concept of solid dispersion, criteria for drug selection, advantage and disadvantage, characterization, and application.

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