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Haq, Abrarul
- Formulation, Optimization and Evaluation of Drotaverine HCl Mini Tablet
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1 Department of Pharmaceutics, Ali-Allana College of Pharmacy Akkalkuwa, Dist.: Nandurbar (425415), Maharashtra, IN
1 Department of Pharmaceutics, Ali-Allana College of Pharmacy Akkalkuwa, Dist.: Nandurbar (425415), Maharashtra, IN
Source
Asian Journal of Pharmacy and Technology, Vol 12, No 1 (2022), Pagination: 6-12Abstract
The aim of present research was to develop a mini tablet of Drotaverine hydrocholoride. Mini tablets of Drotaverine hcl were prepared by using various polymers, such as gellan gum and carbopol 940. Mini tablets were evaluated for weight variation, hardness, thickness, friability, drug content, and in-vitro dissolution studies. The prepared mini tablets exhibited satisfactory physic-chemical characteristics. All prepared batches shown good in-vitro dissolution studies. The best result from optimized batches is of F5 which gives drug release 97.72% in 12 h time periods.Keywords
Drotaverine Hcl, Mini Tablet, Optimization, Gellan Gum, Direct Compression
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