Asian Journal of Pharmacy and Technology

A. Elumalai ¹, V. Naresh ¹, M. Chinna Eswaraiah ¹, P. Narendar ¹, Raj Kumar ¹

Affiliations
1 Department of Pharmacognosy, Anurag Pharmacy College, Ananthagiri (V), Kodad(M), Nalgonda (Dt), Andhra Pradesh, 508 206, IN

Abstract

The antiulcer activity of ethanolic extract of Couroupita guianensis leaves (EECG) was investigated in pylorus ligation and ethanol induced ulcer models in experimental rats. In both models the common parameter determined was ulcer index. Ethanolic extract of Couroupita guianensis at a dose of 150 and 300mg/kg produced significant inhibition of the gastric lesions induced by pylorus ligation induced ulcer and ethanol induced gastric ulcer. The extract (150mg/kg and 300mg/kg) showed significant (p<0.05) reduction in gastric volume, free acidity and ulcer index as compared to control. This present study indicates that EECG have potential anti-ulcer activity in both models. These results may further suggest that the extract was found to possess antiulcerogenic as well as ulcer healing properties, which might be due to its antisecretory activity.

Keywords

Ethanolic Extract, Couroupita guianensis, Pylorus Ligation, Ethanol Induced Ulcer Model, Ulcer Index, Ranitidine.

Full Text

     

A. Elumalai ¹, Nikhitha Mathangi ¹, Adarsh Didala ¹, Raju Kasarla ¹, Yetcharla Venkatesh ¹

Affiliations
1 Department of Pharmacognosy, Anurag Pharmacy College, Ananthagiri (v), Kodad(M), Nalgonda (Dt), Andhra Pradesh,- 508 206, IN

Abstract

Herbal drugs are traditional method of treating the diseases in worldwide, the plant having ability to treat the diseases also known as medicinal plant. Several types of medicinal plants are breathing in the nature and effective in different type of diseases. In traditional systems of medicine, different parts (leaves, stems, ischolar_mains and even whole plant) of Ceiba pentandra have been recommended for the treatment of bronchitis, diabetics, diarrhoea, dysentery, skin diseases, arthritis, painful eye diseases, chronic fever, insect bite etc. All parts of this plant have numerous therapeutic activities for the treatment of a variety of diseases. It is known as a rich source of tannins, flavonoids and glycosides. This review highlights the use of Ceiba pentandra for the treatment of different disorders and presents the author's approach to the scientific assessment on Ceiba pentandra as potential source of therapeutic agents.

Keywords

Ceiba pentandra, Diabetics, Diarrhoea, Review.

Full Text