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Dinesh Kumar, P.
- Microwave-Assisted Synthesis, Characterization and Biological Activity of Novel Pyrazole Derivatives
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Authors
Affiliations
1 Department Pharmaceutical Chemistry, Srinivas College of Pharmacy, Mangalore-574142, Karnataka, IN
2 Medicinal Chemistry Research Lab, Bapatla College of Pharmacy, Bapatla-522101, Andhra Pradesh, IN
3 Department Pharmaceutical Chemistry, DCRM Pharmacy College, Inkollu-523167, Andhra Pradesh, IN
4 Department of Pharmaceutics, Rahul Institute of Pharmaceutical Science & Research, Chirala-523157, Andhra Pradesh, IN
1 Department Pharmaceutical Chemistry, Srinivas College of Pharmacy, Mangalore-574142, Karnataka, IN
2 Medicinal Chemistry Research Lab, Bapatla College of Pharmacy, Bapatla-522101, Andhra Pradesh, IN
3 Department Pharmaceutical Chemistry, DCRM Pharmacy College, Inkollu-523167, Andhra Pradesh, IN
4 Department of Pharmaceutics, Rahul Institute of Pharmaceutical Science & Research, Chirala-523157, Andhra Pradesh, IN
Source
Asian Journal of Pharmaceutical Research, Vol 1, No 4 (2011), Pagination: 126-129Abstract
A series of 1-(4-substitutedphenyl)-3-phenyl-1H-pyrazole-4-carbaldehyde 4a-e has been synthesized and tested for their anti-inflammatory and analgesic activities. Formation of the pyrazole derivatives was achieved by treating vilsmeier-haack reagent. The newly synthesized compounds were evaluated for their anti-inflammatory and analgesic activities compared to indomethacin, flufenamic acid and diazepam as standard drugs. The detailed synthesis, spectroscopic and toxicity data are reported.Keywords
Pyrazole, Anti-Inflammatory Activity, Analgesic Activity.- Synthesis of Novel Thiazole Derivatives as Analgesic Agents
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PDF Views:1
Authors
Affiliations
1 Medicinal Chemistry Research Laboratory, Bapatla College of Pharmacy, Bapatla-522101, (A.P), IN
2 Medicinal Chemistry Research Laboratory, M.N.R. College of Pharmacy, Sangareddy-502294, (A.P), IN
1 Medicinal Chemistry Research Laboratory, Bapatla College of Pharmacy, Bapatla-522101, (A.P), IN
2 Medicinal Chemistry Research Laboratory, M.N.R. College of Pharmacy, Sangareddy-502294, (A.P), IN