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Gayatri, Mahale
- Review on Microsponges a Novel Drug Delivery System
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1 Pravara Rural College of Pharmacy, Pravaranagar A/P: Loni 413736, Tal - Rahata, Dist: A. Nagar, IN
1 Pravara Rural College of Pharmacy, Pravaranagar A/P: Loni 413736, Tal - Rahata, Dist: A. Nagar, IN
Source
Asian Journal of Pharmaceutical Research, Vol 12, No 3 (2022), Pagination: 241 - 248Abstract
Bottom of Form Microparticulate drug delivery systems have shown a good interest within the pharmaceutical space. they permit the rise of drug therapeutic effectiveness and therefore the reduction of aspect effects. during this context, microsponges represent a brand new model of porous uu microspheres, which permit the defense of a good vary of active agents. Microsponge drug delivery system (MDS) was developed to deliver the pharmaceutical ingredients efficiently at the positioning of administration at a restricted dose. MDS is predicated on pore size of sponges. The action of microsponges lasts up to 12 hours. A microsponge's delivery system could be a extremely cross-linked, porous, chemical compound microsphere, chemical compound system consisting of porous microspheres that may entrap and unleash them into the skin over long amount. This delivery system provides extended release with reduced irritation, higher tolerance, improved thermal, physical and chemical stability. Microsponges area unit ready by many technique utilization emulsion system or by suspension chemical process into a liquid-liquid system. Microsponges will entrapped numerous style of drug and incorporated in formulation like cream, powder, gels, and lotions. Topical preparation have some disadvantages like unpleasant odour, oiliness and skin irritation and fail to achieve the circulation this drawback is overcome by microsponges delivery system.
Keywords
Microsponges, Drug delivery, Topical application
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