Asian Journal of Pharmaceutical Research

Hisham A. Abbas ¹, Fathy M. Serry ¹, Eman M. EL-Masry ¹

Affiliations
1 Department of Microbiology and Immunology, Zagazig University, Zagazig, EG

Abstract

Biofilm-associated infections are persistent and difficult to treat due to the multifactorial antimicrobial resistance. Sugar alcohols have a significant inhibitory effect on dental biofilms. They can reduce the amount of dental plaque and the extracellular polysaccharide (glucans) and intracellular matrix production. The interference with the production of glucans could decrease the extracellular matrix component of mixed oral biofilms.

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