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Authors
Affiliations
1 Department of Pharmacology, Bellamkonda Institute of Technology and Sciences, Podili, IN
2 Department of Pharm. Chemistry, QIS College of Pharmacy, Ongole, IN
Source
Asian Journal of Pharmaceutical Research, Vol 7, No 2 (2017), Pagination: 88-93
Abstract
The present study is carried out to investigate the anti-inflammatory potential of Ethanolic extract of Basella alba (BA). Anti-inflammatory activity was evaluated by using Egg Albumin, Turpentine Oil and Formaldehyde as phlogistic agents. The animals were treated with doses 250mg/kg and 500mg/kg of extract and Diclofenac Sodium at a dose of 10mg/kg is used as a standard drug. The BA showed a significant anti-inflammatory activity in a dose dependent manner in all the models when compared with the standard treatment. The extract (500mg/kg) exhibited maximum antiinflammatory activity i.e., 46.25%, 44.30%, 46.40% (P<0.001) like standard Diclofenac 47.02%, 46.50%, 48.57% in Egg albumin, Turpentine oil and Formaldehyde induced methods respectively. Based on the above results, we conclude that the BA has significant anti-inflammatory activity and might prove efficacious for further design and development of agents with significant biological activity.
Keywords
Basella alba, Anti-Inflammatory Activity, Phlogistic Agents.
