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Parkhe, Abhijeet G.
- Current Therapeutic Targets for Neuropathic Pain
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Authors
Khemchand R. Surana
1,
Abhijeet G. Parkhe
2,
Eknath D. Ahire
3,
Anuprita R. Pawar
1,
Survarna Khairnar
4,
Sunil K. Mahajan
5,
Dhananjay M. Patil
6,
Deepak D. Sonawane
6,
Sanjay J. Kshirsagar
3
Affiliations
1 Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, IN
2 Bharati Vidhyapeeth College of Pharmacy, Belapur, Navi Mumbai, IN
3 Department of Pharmaceutics, MET’s, Institute of Pharmacy, BKC, Adgaon, Nashik – 3, IN
4 Department of Pharmacology, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, IN
5 Department of Pharmaceutical Chemistry, MGV’s Pharmacy College, Panchvati, Nashik, IN
6 Department of Pharmaceutics, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, IN
1 Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, IN
2 Bharati Vidhyapeeth College of Pharmacy, Belapur, Navi Mumbai, IN
3 Department of Pharmaceutics, MET’s, Institute of Pharmacy, BKC, Adgaon, Nashik – 3, IN
4 Department of Pharmacology, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, IN
5 Department of Pharmaceutical Chemistry, MGV’s Pharmacy College, Panchvati, Nashik, IN
6 Department of Pharmaceutics, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, IN
Source
Asian Journal of Pharmaceutical Research, Vol 12, No 1 (2022), Pagination: 96 - 104Abstract
Nociceptive ache signals the frame to capability or real tissue harm. By contrast, neuropathic ache, which ends from damage or harm to the worried system, persists lengthy in spite of everything symptoms and symptoms of the authentic damage have disappeared. This kind of maladaptive ache affords a full-size scientific problem, because it responds poorly or unpredictably to classical analgesics. There is likewise no single, uniformly well- tolerated drug this is reliably helpful. Neuropathic ache withinside the popular populace is expected to have a occurrence ranging among 3% and 17%. Most of the remedies for neuropathic ache have slight efficacy and gift aspect consequences that restriction their use; therefore, different healing strategies are wished for patients. In this article, the contemporary trendy of care treatment, the rising pharmacological strategies until date, and the preclinical research on novel promising healing alternatives could be reviewed.
Keywords
Neuropathic pain, Inflammation, Drugs acting on neuropathic pain, Cannabinoid receptor
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