Asian Journal of Pharmaceutical Research

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Daily Dose, in a Dot


Affiliations
1 Dept. of Pharmacology, Sardar Patel College of Pharmacy, Anand, India
2 Dept. of Quality Assurance, Sardar Patel College of Pharmacy, Anand, India
3 Principal, Dept. of Pharmacology, Sardar Patel College of Pharmacy, Anand, India
     

   Subscribe/Renew Journal


Iodine is a vital micronutrient required at all stages of life. It is concentrated in thyroid gland for the synthesis of thyroid hormones. Drinking water and crops grown in iodine rich soil are the most important sources of iodine. Leeching of iodine and ultra-violate radiation contribute to the development of iodine deficiency disorders (IDD). It mainly affects infant and children due to maternal iodine deficiency. A deficiency of thyroid hormone from any cause will lead to severe retardation of growth and maturation of almost all organ systems. In Asia, IDD is continuously increased from 4% to 50% among school children. Number of treatments are available for the IDD. However, the tribal population is considered to be one of the most disadvantaged groups in accessing the health care services and various other health policies. The Nashik based Neelvasant medical foundation & research centre established a new technique for the tribal women. They have made iodine patches in the form of different coloured bindis and distributed it among the tribal women. Around 80-90per cent of Indian women wear bindis. It is the best way to deal with the problem. The project is already started and ready to enter in its second phase. Where, larger number of population are covered.

Keywords

Iodine, Iodine Deficiency Disease (IDD), Iodine Patches, Lifesaving Dot.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Dhaar GM, Robbani I. Foundations of Community Medicine. India: Reed Elsevier; 2008. Nutritional problems of mothers and children. pp. 272–280.

  • Detels R, Holland WW, Mc Ewen HJ, Omenn GS. Oxford Textbook of Public Health.3. Oxford University Press; 1977. Endocrine and metabolic disorders; pp. 1114–1115.

  • Khurana I. Textbook of Medical Physiology. India: Reed Elsevier; 2006. Endocrinal System; pp. 710–715.

  • Pal GK. Textbook of Medical Physiology. India: Ahuja Publishing House; 2007. Endocrine Physiology; p. 346.

  • Zimmermann MB. Iodine deficiency. Endocr Rev 2009;30:376-408.

  • Nicola JP, Basquin C, Portulano C, Reyna-Neyra A, Paroder M, Carrasco N. The Na+/I- symporter mediates active iodide uptake in the intestine. Am J Physiol Cell Physiol 2009;296:C654-62.

  • Eskandari S, Loo DD, Dai G, Levy O, Wright EM, Carrasco N. Thyroid Na+/I- symporter. Mechanism, stoichiometry, and specificity. J BiolChem 1997;272:27230-8.

  • Oppenheimer JH, Schwartz HL, Surks MI. Determination of common parameters foiodothyronine metabolism and distribution in man by noncompartmental analysis. J ClinEndocrinolMetab 1975;41:319-24.

  • Jameson JL, DeGischolar_main LJ. Endocrinology adult and pediatric: the thyroid gland. 6th ed. Philadelphia; Saunders, 2013.

  • De La Vieja A, Dohan O, Levy O, Carrasco N. Molecular analysis of the sodium/iodide symporter: impact on thyroid and extrathyroid pathophysiology. Physiol Rev2000;80:1083-105.

  • Morton ME, Chaikoff IL, Rosenfeld S. Inhibiting effect of inorganic iodide on the formation in vitro of thyroxine and diiodotyrosine by surviving thyroid tissue. J BiolChem 1944;154:381-7.

  • Wolff J, Chaikoff IL. Plasma inorganic iodide as a homeostatic regulator of thyroid function. J BiolChem 1948;174:555-64.

  • Wolff J, Chaikoff IL, Goldberg RC. The temporary nature of the inhibitory action of excess iodine on organic iodine synthesis in the normal thyroid. Endocrinology 1949;45:504-13.

  • Patrick L. Iodine: Deficiency and therapeutic considerations. Altern Med Rev. 2008;13:116–127.

  • UNICEF-ADB-RETA. Reducing Child Malnutrition in Selected Asian Countries. National Strategy to Reduce Child Malnutrition in India. Co-ordinated by Department of Women & Child Development Ministry of HRD, Government of Indian. Administrative Staff College of India Bella Vista, Hyderabad – 500 082 December 1997.

  • Hetzel, BS. The Control of Iodine Deficiency. American Journal of Public Health April 1993; 83(4): 494-5.

  • NándorÁcs, Ferenc G, Bánhidy Andrew E, Czeizel. Congenital Abnormalities and Preterm Birth Related to Maternal Illnesses During Pregnancy. Dordrecht Heidelberg London New York: Springer;2010.

  • Travers CA, Guttikonda K, Norton CA, et al. Iodine status in pregnant women and their newborns: are our babies at risk of iodine deficiency? Med J Aust 2006; 184: 617-20.

  • Abuye C, Berhane. Y. The Goitre rate, its association with reproductive failure, and knowledge of iodine deficiency disorder among women in Ethiopia: cross-section community based study. BMC Public Health 2007; 7: 316.

  • World Health Organization (WHO) ICCIDD, UNICEF, WHO. 2. ICCIDD, UNICEF, WHO: 2001. Assessment of iodine deficiency disorders and monitoring their elimination: A guide for programme managers.

  • Pandav CS. IDD in South East Asia. In: Hetzel BS, Pandav CS, editors. In SOS for a billion: The conquest of Iodine Deficiency Disorders. New Delhi, India: Oxford University Press; 1996. pp. 278.

  • Miller KL, Coen PE, et al. “Effectiveness of skin absorption of tincture of I in blocking radioiodine from the human thyroid gland.” Health Physics, 1989; 56:911-914.

  • A dOt with a mission, 07th August, 2017 http://www.the hindubusinessline.com/catalyst/a-dot-with-a-mission/article7085099.ece


Abstract Views: 546

PDF Views: 0




  • Daily Dose, in a Dot

Abstract Views: 546  |  PDF Views: 0

Authors

Kintu Patel
Dept. of Pharmacology, Sardar Patel College of Pharmacy, Anand, India
Sankalp Patel
Dept. of Quality Assurance, Sardar Patel College of Pharmacy, Anand, India
Samir K. Shah
Principal, Dept. of Pharmacology, Sardar Patel College of Pharmacy, Anand, India

Abstract


Iodine is a vital micronutrient required at all stages of life. It is concentrated in thyroid gland for the synthesis of thyroid hormones. Drinking water and crops grown in iodine rich soil are the most important sources of iodine. Leeching of iodine and ultra-violate radiation contribute to the development of iodine deficiency disorders (IDD). It mainly affects infant and children due to maternal iodine deficiency. A deficiency of thyroid hormone from any cause will lead to severe retardation of growth and maturation of almost all organ systems. In Asia, IDD is continuously increased from 4% to 50% among school children. Number of treatments are available for the IDD. However, the tribal population is considered to be one of the most disadvantaged groups in accessing the health care services and various other health policies. The Nashik based Neelvasant medical foundation & research centre established a new technique for the tribal women. They have made iodine patches in the form of different coloured bindis and distributed it among the tribal women. Around 80-90per cent of Indian women wear bindis. It is the best way to deal with the problem. The project is already started and ready to enter in its second phase. Where, larger number of population are covered.

Keywords


Iodine, Iodine Deficiency Disease (IDD), Iodine Patches, Lifesaving Dot.

References