Abstract Views :222 |
PDF Views:1
Authors
Affiliations
1 Department of Pharmaceutical Analysis and Quality Assurance, Vishnu Institute of Pharmaceutical Education and Research, Vishnupur, Narsapur, Medak, Telangana, IN
Source
Asian Journal of Pharmaceutical Analysis, Vol 7, No 1 (2017), Pagination: 15-17
Abstract
A simple, sensitive, accurate, precise and economical visible Spectrophotometric method was developed and validated for the estimation of Cilazapril in Bulk form. The method is based on the reaction of Cilazapril with MBTH Reagent [3-Methyl-2-Benzothiazolinone Hydrazone] in the presence of Ferric chloride producing greenish yellow colour chromogen which shows maximum absorbance at 402nm against reagent blank. The Chromogen obeyed Beer's law in the concentration range of 10-50 μg/ml for Cilazapril. The results of the analysis have been validated statistically and recovery studies.
Keywords
Cilazapril, MBTH Reagent, Ferric Chloride, Visible Spectrophotometric.
