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Authors
Affiliations
1 Department of Chemistry, Government Vidarbha Institute of Science and Humanities, Amravati 444604, IN
Source
Asian Journal of Pharmaceutical Analysis, Vol 7, No 4 (2017), Pagination: 214-217
Abstract
A novel method has been developed for the synthesis of 2-(3-substitutedamino-2,4-dithiobiuretoformamidino-4-isobutoxyphenyl)-4-methyl-5-carboxy-1,3-thiazoles by the reaction of 2-(3-substitutedthioamidoformamidino-4-isobutoxyphenyl)-4-methyl-5-carboxy-1,3-thiazoles with substituted isothiocyanate in 60% ethanol-acetone. The method provides rapid and easy access to compounds in good yields by using 60% ethanol-acetone medium.
Keywords
2-(3-Substitutedthioamidoformamidino-4-Isobutoxyphenyl)-4-Methyl-5-Carboxy-1,3-Thiazoles, Ethanol, Acetone.
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