Asian Journal of Pharmaceutical Analysis

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Validation of Eugenol in Ethanol by UV Spectrophotometric Method


Affiliations
1 College of Pharmacy (D. Pharm), Degaon, Satara (MH) - 415 004, India
     

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Eugenol is a chief chemical constituent of clove oil and having lots of applications. Thus development of a validated UV spectrophotometric method will always advantageous. The method was validated according to International conference on Harmonization (ICH) guidelines Q2 (R1) with respect to Accuracy, Precision, linearity and range, Ruggedness, Robustness. This method is found to be linear in range between 15-50 μg/ml presenting good correlation coefficient (0.991) showing 98.87 % accuracy.

Keywords

ICH, Accuracy, Precision, Linearity And Range, Ruggedness, Robustness.
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  • Validation of Eugenol in Ethanol by UV Spectrophotometric Method

Abstract Views: 222  |  PDF Views: 2

Authors

Yogita R. Indalkar
College of Pharmacy (D. Pharm), Degaon, Satara (MH) - 415 004, India
N. H. Aloorkar
College of Pharmacy (D. Pharm), Degaon, Satara (MH) - 415 004, India

Abstract


Eugenol is a chief chemical constituent of clove oil and having lots of applications. Thus development of a validated UV spectrophotometric method will always advantageous. The method was validated according to International conference on Harmonization (ICH) guidelines Q2 (R1) with respect to Accuracy, Precision, linearity and range, Ruggedness, Robustness. This method is found to be linear in range between 15-50 μg/ml presenting good correlation coefficient (0.991) showing 98.87 % accuracy.

Keywords


ICH, Accuracy, Precision, Linearity And Range, Ruggedness, Robustness.