Synthesis and Investigation and Microbial Activity of Open Chain of Organo-Selenium Compounds

The target organo-selenium compounds [3-7] were synthesized from the reaction between diethyl malonate and 4-amino benzoyl chloride to produce compound [1], which is react with sodium hydrogen selenide to give corresponding sodium aroylselenide [2], which is react with one of aroyl derivatives as shown in scheme (1) to produce compounds [3-7]. All the synthesized compounds have been investigated using different chemical techniques, such as (H.NMR-spectra, (C.H.N)-analysis, FT.IR-spectra), melting points and biological study.