Ligand Field Parameters of some Transition Metal Ion Complexes of 1-(4- Aminobenzoyl)-2-[1-(5-Chloro-2-Hydroxyphenyl) Ethylidene] Hydrazine and their Anti Bacterial Activity

Potentiometric studies have been carried out on transition metal complexes of Mn⁺², Co⁺², Ni⁺², Cu⁺², Zn⁺² with hydrazones synthesized from 4-amino benzoic- acid hydrazide and 5-chloro-2- hydroxy acetophenone. The dissociation constants of ligand and formation constants of its metal complexes have been determined by Calvin-Bjerrum pH titration technique, as adopted by Irving and Rossotti at 27±0.1^oC and at an ionic strength of 0.1M in 60:40 (v/v) dioxane water medium. The order of the stability of complexes is Cu⁺² > Ni⁺² > Co⁺² > Mn⁺² > Zn⁺² for the ligand ACEH. All the metal complexes screened for their antibacterial activity. The result indicates that the growth of the tested organism was inhibited by most of the compounds.