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Sadananda Maiya, P.
- In Vitro Antioxidant Studies of Momordica Cymbalaria
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Authors
Affiliations
1 Dr. P. Sadananda Maiya Centre for Food Science and Research, Jayanagara, Bengaluru, Karnataka, IN
2 Department of Studies and Research in Chemistry and Centre for Nanoscience Research, Tumkur University, Tumkur, Karnataka, IN
1 Dr. P. Sadananda Maiya Centre for Food Science and Research, Jayanagara, Bengaluru, Karnataka, IN
2 Department of Studies and Research in Chemistry and Centre for Nanoscience Research, Tumkur University, Tumkur, Karnataka, IN
Source
Asian Journal of Bio Science, Vol 8, No 1 (2013), Pagination: 107-116Abstract
Momordica cymbalaria is a well known plant species since ancient times for use in the treatment of various ailments. Recently, it is well documented that this species found to have significant anti-diabetic activity. This investigation was aimed at assessing the hydro-alcoholic extracts of various parts such as aerial parts, fruits and ischolar_mains for their antioxidant activity. Pharmacognosy studies, extraction, phytochemical analysis and in vitro antioxidant activity studies were carried out. The antioxidant activity studies were carried out by ferric ion reducing, ABTS free radical scavenging, nitric oxide scavenging and total antioxidant assays. Ferric ion reducing power of aerial parts extract was found to be higher compared to fruits and ischolar_main extract. However, nitric oxide scavenging activity was found be higher for fruits extract followed by aerial parts and ischolar_mains. The same trend was followed in the cases of ABTS radical scavenging activity and total antioxidant activity. IC50 value of ABTS radical scavenging activity of fruits extract was found to 13 ?g/ml compared to the standard compound Ascorbic acid which has IC50 value of 4.3 ?g/ml. The total antioxidant activity of fruits extract was found to be 95.27 mg equivalents of ascorbic acid per gram. These potential antioxidant activities of the extracts have far reaching implications in further exploring this species for further studies in this direction.Keywords
Momordica Cymbalaria, Plant Extracts, Antioxidant, Free Radical Scavenging
- In Vitro Antioxidant Activity Studies of Artocarpus gomezianus
Abstract Views :663 |
Authors
Affiliations
1 Dr. P. Sadananda Maiya Centre for Food Science and Research, Benguluru (Karnataka), IN
2 Department of Studies and Research in Chemistry, Tumkur University, Tumkur (Karnataka), IN
1 Dr. P. Sadananda Maiya Centre for Food Science and Research, Benguluru (Karnataka), IN
2 Department of Studies and Research in Chemistry, Tumkur University, Tumkur (Karnataka), IN
Source
Asian Journal of Bio Science, Vol 9, No 2 (2014), Pagination: 273-283Abstract
Extraction of fruits, aerial parts and ischolar_mains from Artocarpus gomezianus were subjected for pharmacognostic analysis. Also these parts were subjected tohydro-alcohol (30:70) extraction by soxhlet extraction technique. The raw materials were dried and powdered and analyzed for various parameters. The moisture content was found to be in the range of 4.97 per cent to 11.09 per cent, extractive values - 14.92 per cent to 18.75 per cent, chloroform solubility 1.15 per cent to 6.99 per cent and water solubility ranged between 4.52 per cent to 5.77 per cent. Fluorescence analysis and ash values were also determined. Extraction yields with 30:70 solvents indicate the quantitative idea about some of the proximate components. The results are important in planning the extraction, phytochemical analysis and determination of their various beneficial biological activities. The study was undertaken to evaluate qualitatively for the contents of carbohydrates, glycosides, saponins, alkaloids, flavonoids, phenolics, tannins, Phytosterols, Triterpenoids, oils and fats present in the extracts from the Fruit, Aerial parts and Roots of Artocarpus gomezianus. The extracts when tested qualitatively for various phytochemicals, they found to contain carbohydrates, Glycosides, alkaloids, tannins, phytosterols and Triterpinoids. However, they do not contain saponins, oils and fats. Quantitative estimation of extracts for total phenols and total flavonoids reveals that most parts contain reasonably higher amounts. The results clearly demonstrate that the extracts can be considered for further studies which evaluate the biological activity such as antioxidant activities. Antioxidant assays such as Nitric oxide scavenging assay, Ferric ion reducing activity assay, ABTS free radical scavenging activity assay and total antioxidant assays were performed to ascertain the potency of the extracts. Fruit extract of Artocarpus gomezianus was found to have maximum ferric ion reducing property than other parts studied. Nitric oxide scavenging activity was found to be higher in fruit followed by aerial and ischolar_main parts. ABTS radical scavenging activity of aerial part extract is found to be 5 mg/ml compared to the standard ascorbic acid with 4 mg/ml. The total antioxidant activity was found to be significantly high for the extract from fruit part than the extracts from aerial and ischolar_main parts. It is clear from the studies that the extracts of aerial parts, fruits and ischolar_mains possess potentially beneficial antioxidant activities. In view of their use in ancient medicine coupled with the recent understandings of these plant species, they may be considered for further exploration as they may yield very potent nutraceuticals.Keywords
Artocarpus gomezianus, Plant Extracts, Antioxidant, Free Radical Scavenging.References
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