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Authors
Affiliations
1 Jacobs University Bremen, Campus Ring 1, D-28759 Bremen, DE
Source
Journal of Advances in Engineering Sciences, Vol 1, No 2 (2008), Pagination: 13-22
Abstract
Nanotechnology is expected to be one of the future key technologies. One approach to realize nano-objects is by self-assembly and involves an understanding of interaction on a molecular level. Numerous examples are found in nature as self-organization on a nanometer scale is a fundamental building principle of life. Here we discuss recent advances for characterization of natural nano channels using a microfluidic setup for high- throughput and parallelized processing, making biological channels accessible for true engineering applications. As an example we focus on the permeation of antibiotics through specific channels, a current problem in drug- screening technology. For that we miniaturize a classical artificial bilayer set-up, automating the formation of planar membranes to host channels and combining this with microfluidics.
