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Paul, Ranu
- An Analysis of the Dynamics of a Cancerous Tumour Model with Targeted Chemotherapy
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Authors
Affiliations
1 Department of Mathematics, Gauhati University, Guwahati – 781014, Assam, IN
1 Department of Mathematics, Gauhati University, Guwahati – 781014, Assam, IN
Source
Asian Journal of Pharmaceutical Research and Health Care, Vol 12, No 3 (2020), Pagination: 130-140Abstract
We have analyzed a model of Lotka-Volterra type interacting between immune cell-tumour cell-normal cells, where control policy is applied in terms of targeted chemotherapy. We determined conditions for the local stability of all the equilibrium points and global stability condition for the tumour free equilibrium point, including the feasibility of the solution. Further, we have discussed the possibility of Hopf bifurcation at each equilibrium point. Numerical simulation was carried out to observe the qualitative behaviour of the system as the control parameter is varied.
Keywords
Global Stability, Hopf Bifurcation, Lotka-Volterra Type, Targeted Chemotherapy.Full Text
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