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Dixit, Alok
- Analysis of Prescribing Pattern, Efficacy and Adverse Drug Reactions of Anti-diabetic Agents in Type-2 Diabetic Patients at a Tertiary Care Teaching Hospital
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Affiliations
1 Department of Pharmacology, Uttar Pradesh University of Medical Sciences Saifai, Etawah – 206130, Uttar Pradesh
2 Department of Pharmacology, Uttar Pradesh University of Medical Sciences Saifai, Etawah – 206130, Uttar Pradesh, IN
3 Department of Medicine, Uttar Pradesh University of Medical Sciences Saifai, Etawah – 206130, Uttar Pradesh, IN
1 Department of Pharmacology, Uttar Pradesh University of Medical Sciences Saifai, Etawah – 206130, Uttar Pradesh
2 Department of Pharmacology, Uttar Pradesh University of Medical Sciences Saifai, Etawah – 206130, Uttar Pradesh, IN
3 Department of Medicine, Uttar Pradesh University of Medical Sciences Saifai, Etawah – 206130, Uttar Pradesh, IN
Source
Asian Journal of Pharmaceutical Research and Health Care, Vol 13, No 2 (2021), Pagination: 125-131Abstract
Prescription pattern analysis provides guidance to utilize available drugs rationally. Diabetes is a chronic, hyperglycaemic metabolic disorder with subsequent complications. The aim of present study is to analyse prescribing pattern, efficacy and Adverse Drug Reactions (ADRs) of Anti-diabetic Drugs (ADDs) in our tertiary care teaching institute. A prospective analytical study was conducted and demographical details, investigations (fasting, postprandial blood glucose and HbA1C at every 3 months, LFT, Lipid profile and KFT) and prescriptions were collected from 135 uncomplicated Type-2 diabetic patients visiting Medicine OPD over a period of 18 months. Prescriptions were collected and ADDs, fixed dose combinations (FDCs), other medicines used and ADRs were also recorded. Data collected was analysed using t-test and chi-square test. 94 (69.63%) patients were of 41-60 years age group with mean BMI of 26.63 ± 3.26. Fasting, postprandial blood glucose and HbA1c initially and at 18 months were 193 ± 65, 284 ± 78, 9.2 ± 2.3 and 107 ± 15, 163 ± 23, 6.5 ± 0.6 respectively with a significant reduction in mean fasting, postprandial blood glucose and HBA1c at 18 months (P<0.0001). Total drugs prescribed were 331, ADDs 222 (67.07%), FDCs 61 (18.43%), generic drugs 270 (81.57%), drugs from National list of Essential Medicines 259 (78.25%), injectables 2 (1.48%), other group of drugs 48 (14.50%) and ADRs 21 (15.56%). Average drugs per prescription were 2.45 and ADDs 1.64. The present study showed that the prescriptions were rational, drugs used were efficacious and ADRs mild and transient.Keywords
Antidiabetic Drugs, NLEM, Prescribing PatternFull Text
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