Asian Journal of Pharmaceutical Research and Health Care

Open Access Open Access  Restricted Access Subscription Access

Gas Chromatography-mass Spectroscopic Investigation of Petroleum Ether Concentrates of Desert Date/Ingudi (Balanites aegyptiaca Linn. Delile) w. s. r. Wound Mending


Affiliations
1 Department of Dravyaguna, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi – 221005, Uttar Pradesh, India
2 Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi – 221005, Uttar Pradesh, India
 

The idea behind this research work is to investigate the phytochemical constituents from Petroleum ether concentrate of Ingudi (Balanites aegyptiaca L. Delile) seeds utilizing GC-MS (Gas chromatography-mass spectroscopy) and to clarify the customary utilization of Ingudi oil as an effective injury mending specialist. A sum of 100 gm Ingudi seeds coarsely powdered, air-dried were macerated and extracted in Petroleum ether (1 Liter) at 60–80°C for 72 hours. The petroleum ether concentrate was exposed to GC-MS investigation. The GC-MS examination of the Petroleum ether concentrates of Ingudi shows presence of seven functional groups which are alcohol, carboxylic corrosive, ester, ether, silyl ether, and phenol. The compounds present are Tetradecamethylcycloheptasiloxane, Feruloyl-caffeoyl-glycerol, Decamethylcyclopentasiloxane, 17-Octadecynoic Acid, 2-Hydroxy Succinic Acid, Dec-4-Anyl Undecyl Ester, Stigmasterol Trimethylsilyl Ether, Succinic corrosive butyl ester 4-hydroxy-12–methyl-tridecyl ester. The extract shows antibacterial, antioxidant, wound recuperating action, antifungal, immunomodulatory, antistatic, emollient, humectants, anti-provocative, hypocholesterolemic, malignancy preventive, hepatoprotective, nematicide, insectifuge, antihistaminic, antieczemic, antiacne, 5-Alpha reductase inhibitor, antiandrogenic, antiarthritic, anticoronary, antipsychotic, insectifuge, antimicrobial movement, larvicidal, thyroid hindering action, and hypoglycemic action. This examination assists to anticipate the equation and structure of dynamic particles which can be utilized as a decent and effective injury recuperating operator. This outcome additionally improves the customary use of Ingudi oil. The medicinal use of this oil was reported in Sanskrit literature (Abhigyan shakuntalam).

Keywords

GC-MS, Ingudi, Seed, Balanites aegyptiaca, Abhigyan Shakuntalam, Petroleum ether extract
User
Notifications
Font Size

  • Viraj AS. Delhi. Rajpal and sons. 2020; p. 66–67

  • Chapagain B, Wiesman Z. Variation in diosgenin level in seed kernels among different provenances of Balanites aegyptiaca Del (Zygophyllaceae) and its correlation with oil content. African Journal of Biotechnology. 2005; 4(11): 6170EF211704.

  • Rao KP, Sreeramulu SH. Ethnobotany of selected medicinal plants of Srikakulam district, Andhra Pradesh. Ancient Science of Life. 1985 Apr; 4(4): 238-244.

  • Bhatnagar LS, Singh VK, Pandey G. Medico-botanical studies on the flora of Ghatigaon forests, Gwalior, Madhya Pradesh. J Res Indian Med. 1973; 8(2):67-100.

  • Shah GL, Menon AR, Gopal GV. An account of the Ethnobotany of Saurashtra in Gujarat state (India). Journal of Economic and Taxonomic Botany. 1981; 2:173–82. https://doi.org/10.18178/ijch.2016.2.4.059

  • Rezapour-Lactoee A, Yeganeh H, Ostad SN, Gharibi R, Mazaheri Z, Ai J. Thermoresponsive polyurethane/siloxane membrane for wound dressing and cell sheet transplantation: In-vitro and in-vivo studies. Materials Science and Engineering: C. 2016 Dec 1; 69:804–14. https://doi.org/10.1016/j.msec.2016.07.067. PMid:27612775

  • Compton DL, Laszlo JA, Evans KO. Antioxidant properties of feruloyl glycerol derivatives. Industrial Crops and Products. 2012 Mar 1; 36(1):217–21. https://doi.org/10.1016/j.indcrop.2011.09.009

  • Saad AM. Determination of secondary metabolites products by Trichoderma horzianum and evaluate antimicobial activity. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2016; 7(3):105–22.

  • Tyagi T, Agarwal M. Phytochemical screening and GC-MS analysis of bioactive constituents in the ethanolic extract of Pistia stratiotes L. and Eichhorniacrassipes (Mart.) solms. Journal of Pharmacognosy and Phytochemistry. 2017; 6(1):195–206.

  • Bechkri S, Berrehal D, Semra Z, Bachari K, Kabouche A, Kabouche Z. Composition and biological activities of seeds oils of two Crataegus species growing in Algeria. Journal of Materials and Environmental Sciences. 2017; 8(5):1526–30.

  • Mahmud PI, Yaacob W, Ibrahim N, Bakar MA. Antibacterial activity and major constituents of polyalthiacinnamomea basic fraction. Sains Malaysiana. 2018 Sep 1; 47(9):2063–71. https://doi.org/10.17576/jsm-2018-4709-14

  • Patil A, Jadhov V. GC-MS analysis of bioactive components from methanol leaf extract of Toddaliaasiatica (L.). International Journal of Pharmaceutical Sciences Review and Research. 2014; 29(1):18–20.

  • Cycloheptasiloxane, 107-50-6 [Internet]. [cited 2020 Aug 24]. Available from: http://www.thegoodscentscompany.com/data/rw1331301.html

  • Dekant W, Klaunig JE. Toxicology of decamethylcyclopentasiloxane (D5). Regulatory Toxicology and Pharmacology. 2016 Feb 1; 74:S67–76. https://doi.org/10.1016/j.yrtph.2015.06.011. PMid:26111607

  • Dandekar R, Fegade B, Bhaskar VH. GC-MS analysis of phytoconstituents in alcohol extract of Epiphyllum oxypetalum leaves. Journal of Pharmacognosy and Phytochemistry. 2015 May 1; 4(1): 148-154.

  • Rahuman AA, Gopalakrishnan G, Ghouse BS, Arumugam S, Himalayan B. Effect of Feronia limonia on mosquito larvae. Fitoterapia. 2000 Sep 1; 71(5):553–5. https://doi.org/10.1016/S0367-326X(00)00164-7

  • Yang LH. Antifouling compounds from the marine sponge Acanthella cavernosa and its associated microbes [Internet] (Doctoral Dissertation). Available from: http://hdl.handle.net/1783.1/2775

  • Panda S, Jafri M, Kar A, Meheta BK. Thyroid inhibitory, antiperoxidative and hypoglycemic effects of stigmasterol isolated from Butea monosperma. Fitoterapia. 2009 Mar 1; 80(2):123–6. https://doi.org/10.1016/j.fitote.2008.12.002. PMid:19105977

  • Dev SK, Choudhury PK, Srivastava R, Sharma M. Antimicrobial, anti-inflammatory and wound healing activity of polyherbal formulation. Biomedicine and Pharmacotherapy. 2019 Mar 1; 111:555–67. https://doi.

  • org/10.1016/j.biopha.2018.12.075. PMid:30597309

  • Süntar I, Akkol EK, Nahar L, Sarker SD. Wound healing and antioxidant properties: Do they coexist in plants?. Free Radicals and Antioxidants. 2012 Apr 1; 2(2):1–7. https://doi.org/10.5530/ax.2012.2.2.1

  • Moncrieff G, van Onselen J, Young T. The role of emollients in maintaining skin integrity. Wounds UK. 2015 Mar 1; 11(1).

  • Daeschlein G. Antimicrobial and antiseptic strategies in wound management. International Wound Journal. 2013 Dec; 10(s1):9–14. https://doi.org/10.1111/iwj.12175. PMid:24251838


Abstract Views: 229

PDF Views: 93




  • Gas Chromatography-mass Spectroscopic Investigation of Petroleum Ether Concentrates of Desert Date/Ingudi (Balanites aegyptiaca Linn. Delile) w. s. r. Wound Mending

Abstract Views: 229  |  PDF Views: 93

Authors

Sanjeev Kumar
Department of Dravyaguna, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi – 221005, Uttar Pradesh, India
S. Krishnamoorthi
Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi – 221005, Uttar Pradesh, India
K. N. Dwivedi
Department of Dravyaguna, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi – 221005, Uttar Pradesh, India

Abstract


The idea behind this research work is to investigate the phytochemical constituents from Petroleum ether concentrate of Ingudi (Balanites aegyptiaca L. Delile) seeds utilizing GC-MS (Gas chromatography-mass spectroscopy) and to clarify the customary utilization of Ingudi oil as an effective injury mending specialist. A sum of 100 gm Ingudi seeds coarsely powdered, air-dried were macerated and extracted in Petroleum ether (1 Liter) at 60–80°C for 72 hours. The petroleum ether concentrate was exposed to GC-MS investigation. The GC-MS examination of the Petroleum ether concentrates of Ingudi shows presence of seven functional groups which are alcohol, carboxylic corrosive, ester, ether, silyl ether, and phenol. The compounds present are Tetradecamethylcycloheptasiloxane, Feruloyl-caffeoyl-glycerol, Decamethylcyclopentasiloxane, 17-Octadecynoic Acid, 2-Hydroxy Succinic Acid, Dec-4-Anyl Undecyl Ester, Stigmasterol Trimethylsilyl Ether, Succinic corrosive butyl ester 4-hydroxy-12–methyl-tridecyl ester. The extract shows antibacterial, antioxidant, wound recuperating action, antifungal, immunomodulatory, antistatic, emollient, humectants, anti-provocative, hypocholesterolemic, malignancy preventive, hepatoprotective, nematicide, insectifuge, antihistaminic, antieczemic, antiacne, 5-Alpha reductase inhibitor, antiandrogenic, antiarthritic, anticoronary, antipsychotic, insectifuge, antimicrobial movement, larvicidal, thyroid hindering action, and hypoglycemic action. This examination assists to anticipate the equation and structure of dynamic particles which can be utilized as a decent and effective injury recuperating operator. This outcome additionally improves the customary use of Ingudi oil. The medicinal use of this oil was reported in Sanskrit literature (Abhigyan shakuntalam).

Keywords


GC-MS, Ingudi, Seed, Balanites aegyptiaca, Abhigyan Shakuntalam, Petroleum ether extract

References





DOI: https://doi.org/10.18311/ajprhc%2F2020%2F25653