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Authors
Affiliations
1 Department of Zoology, DAV (P.G.) College, Dehradun-248001, IN
Source
Toxicology International (Formerly Indian Journal of Toxicology), Vol 16, No 2 (2009), Pagination: 117-119
Abstract
Di-n-butyl phthalate is a low volatile chemical added to plastic, paint, glue, hair spray, toys and house hold products. Human being and animal are exposed to di-n-butyl phthalate through air, water and food contamination in the environment. For present study, a group of six infection free rats were acclimatized under laboratory condition and divided in to two groups three in each. Group I (control) albino rat fed commercial feed with corn oil. Group II albino rats were given 50mg/kg/day di-n-butyl phthalate with corn oil for 2 week. The study revealed that haemaglobin gm%, RBC and lymphocytes were decreased, 14.6% to 7.8%, 6.17-4.19 millions/cmm and 78 to 44% respectively. However, number of neutrophils were increased .A significant decrease in cholesterol level (121- 51 mg/dl), protein (10 to 4.6 gm/dl) and glucose was observed in di-n-butyl phthalate exposed rats.
Keywords
Cholesterol, DBP, lymphocyte and neutrophil
