Research Journal of Pharmacy and Technology

Yahya Ebrahimi ¹, Afshin Hasanvand ², Ali Valibeik ², Farzad Ebrahimi ³, Saber Abbaszadeh ²

Affiliations
1 Department of Cardiology, Lorestan University of Medical Sciences, Khorramabad, IR
2 Lorestan University of Medical Sciences, Khorramabad, IR
3 Biotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, IR

Abstract

Cardiovascular disease is one of the most important causes of death in industrialized countries. Hyperlipidemia is a major risk factor for cardiovascular disease. Medicinal plants and their active ingredients have long been addressed for the treatment of lipidemia and associated complications. Recently, the use of medicinal plants has become more prevalent due to the side effects of chemical drugs. Therefore, in this study, the most important effective medicinal herbs on hyperlipidemia were reviewed. Based on the results, medicinal plants such as Medicago sativa, Trigonella foenum graecum L., Cynara scolymus, Silybum marianum L., Glycine max L., Allium sativum L., Rheum ribes L. Basil, Crocus sativus Citrus medica, Lavandula stoechas, Melissa officinalis, Black cardamom, Cinnamomum cassia, Phyllanthus emblica, Punica granatum L and Elettaria cardamomum are among the most important plants that are used for hyperlipidemia. The most important active ingredients of the plants include beta-carotene, L-cavanine, diosgenin, yamogenin, trigonelline, sarsapogenin, fenugreekine, smilagenin, cinnarine and luteolin, silymarin, purerine, comstrole and genistein, allicin, oxalic acid, cycic acid, beta-glucogaline and renin. Bioactive compounds such as Beta-Carotene and L-Cavanine، Diosgenin, Yamogenin, Trigonelline, Sarsapogenin, Fenugreekine, Smilagenin، Cinnarine and Luteolin, sylimarin, Pourin, Comstrole and Genistein, Allicin, Oxalic Acid, Cinic Acid, Beta Glucogaline and Renin are among the most important compounds of these herbs. In the case of conduction of pharmacological studies on the active ingredients of the medicinal plants that are effective on hyperlipidemia and confirmation of their efficacy, they can be used as hypolipidemic drugs.

Keywords

Cardiovascular Disease, Hyperlipidemia, Herbal Medicine.

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