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Indira Muzib, Y.
- Assessment of Hypolipidemic and Antioxidant Activity of Herbal Concoction against Triton WR-1339 Induced Hyperlipidemia in Experimental Animals
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Authors
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1 Institute of Pharmacentical Technology, Sri Padmavathi Mahila Visva Vidyalayam, Tirupati. AP, IN
2 Department of Pharmacology, Sri Padmavathi School of Pharmacy, Tiruchanoor, AP, IN
1 Institute of Pharmacentical Technology, Sri Padmavathi Mahila Visva Vidyalayam, Tirupati. AP, IN
2 Department of Pharmacology, Sri Padmavathi School of Pharmacy, Tiruchanoor, AP, IN
Source
Research Journal of Pharmacy and Technology, Vol 12, No 2 (2019), Pagination: 615-620Abstract
Hyperlipidemia and high levels of reactive oxygen species in the body are key factors for the development of cardiovascular diseases such as atherosclerosis. The present study was designed to investigate the Hypolipidemic and antioxidant activity of an herbal concoction prepared from leaves of Artocarpus heterophyllus, Mimusops elengi and Talinum portulacifolium. Hyperlipidemia is induced in rats by Triton WR-1339. The concoction showed significant reduction in all serum lipid parameters, together the results showed increase in antioxidant levels and decrease in proxidant levels. Fortunately when histopathology of carotid artery is observed indicating that the concoction can also exert antithrombotic activity to some extent.Keywords
Hypolipidemic, Antioxidant, Antithrombotic, Artocarpus heterophyllus, Mimusops elengi, Talinum portulacifolium.
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