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Al-Kraity, Wijdan Rajh Hamza
- Assessment of Cyclophilin-A Level in Women With Heart Disease After Menopause
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Authors
Affiliations
1 Biology Department, University of Kufa, IQ
1 Biology Department, University of Kufa, IQ
Source
Research Journal of Pharmacy and Technology, Vol 10, No 6 (2017), Pagination: 1675-1678Abstract
In the current study, Seventy menopausal women have CHD were admitted to the coronary care unit of AL-Sader teaching hospital in AL-najaf AL-Ashraf during the period from January to April/2016 for the ages were ranging from 40 to 69 years old. The samples were divided into three groups (SA 25, UA 22, AMI 23), while the healthy group was composed of 20.The current study indicated a significant increase(p<0.05) in serum CYPA of CHD compared with healthy group, while a significant decrease (P<0.05)in serum E2 concentration of CHD compared with healthy group. The results also revealed a significant increase(p>0.05)of serum CYP-A concentration in AMI group as compare with UA group and SA group of CHD, While serum of E2 concentration showed a significantly decrease (p<0.05)in AMI compare with UA and SA groups of CHD. The result showed also a negative correlation between E2 and CYP-A. The present study concluded that E2 and CYP-A were markers for detection and diagnosis of Coronary heart disease in menopausal women.Keywords
Coronary Heart Disease, Menopause, Estradiol and Cyclophilin-A.
- Assessment of CD-147 Level in Women with Coronary Heart Disease after Menopause
Abstract Views :219 |
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Authors
Affiliations
1 Biology Department, University of Kufa, IQ
1 Biology Department, University of Kufa, IQ
Source
Research Journal of Pharmacy and Technology, Vol 11, No 1 (2018), Pagination: 317-320Abstract
In the current study, Seventy menopausal women have CHD were admitted to the Coronary Care Unit of AL-Sadder Teaching Hospital in AL-najaf AL-Ashraf during the period from January to April/2016 for the ages were ranging from 40 to 69 years old. The samples were divided into three groups (SA 25, UA 22, AMI 23), while the healthy group was composed of 20.The current study indicated a significant increase(p<0.05) in serum CD147 of CHD compared with healthy group, while a significant decrease (P<0.05)in serum E2 concentration of CHD compared with healthy group. The results also revealed a significant increase (p>0.05)of serum CD147concentration in AMI group as compare with UA group and SA group of CHD, While serum of E2 concentration showed a significantly decrease (p<0.05)in AMI compare with UA and SA groups of CHD. The result showed also a negative correlation between E2 and CD147.Keywords
Coronary Heart Disease, Menopause, Estradiol and CD147.References
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- Effect Antioxidant and Serotonin Level in the Sera on Type II Diabetes Mellitus Males Patients and Compare with Control Group
Abstract Views :156 |
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Authors
Affiliations
1 Department of the Pathological Analysis Techniques, College of Al-Toosi University, IR
2 Department of Medicine, Najaf Iraq, IQ
1 Department of the Pathological Analysis Techniques, College of Al-Toosi University, IR
2 Department of Medicine, Najaf Iraq, IQ
Source
Research Journal of Pharmacy and Technology, Vol 12, No 5 (2019), Pagination: 2453-2460Abstract
The study is intended to asses serum levels of Serotonin, malondialdehyde (MDA) and glutathione (GSH) in type 2 diabetic mellitus patients in comparison healthy groups of males, also correlation among Serotonin, MDA and GSH of DM patients. The study was conducted on selected 60 type 2 diabetic patients of males that attending to the diabetes mellitus center in Al-Sadder Teaching City in Al- Najaf province, Iraqi and a group of 60 apparently healthy subjects of males were included as a control group. The D M patients are divided into three groups of ages (15-19y), (20-39y) and (40-60 y). The Study was carried out from June 2018 to October 2018.The patients' age was ranging from 15 to 60 years old. The results also revealed that significant increase (p<0.05) in serum levels Serotonin and MDA in diabetic patients in comparing with healthy groups, while a significant decrease (p<0.05) in serum level GSH in diabetic patients in comparing with healthy groups. The results show that serum Serotonin level no significant (p>0.05) between (20-39y) and (40-60y) ages of D M patients, But there is a significant increase (p<0.05) in these ages groups than the ages (15-19y). The results show that serum MDA level increase significantly (p<0.05) with increasing age of patients and the ages (40-60y) are highly significant(p<0.05) than (20-39-54y) and (15-19y). The results show that serum GSH level no significant (p>0.05) between the ages (20-39y) and (40-60y) groups of D M patients, But there is a significant increase (p<0.05) in the ages (15-19y) than the ages (20-39y) and (40-60y) groups. The results have been shown a significant positive correlation (P<0.05) between serotonin and MDA in DM patients, and a significant negative correlation (P<0.05) between (serotonin and GSH), (MDA and GSH) in DM patients. Conclusion: The present study concluded that Serotonin, MDA and GSH were marker for detection and diagnosis of type 2 diabetic mellitus males patients.Keywords
Type II Diabetes Mellitus, Oxidative Stress, Serotonin, MDA and GSH.References
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- Comparison Visfatin level between Obese and Non Obese, Hypertensive and Normotensive Patients with Ischemic Heart Disease
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Affiliations
1 Department of the Pathological Analysis Techniques, College of Al-Toosi University Najaf, IQ
2 Technical Institute of AL-Diwaniyah, AL-Furat AL-Awsat Technical University, Najaf, IQ
1 Department of the Pathological Analysis Techniques, College of Al-Toosi University Najaf, IQ
2 Technical Institute of AL-Diwaniyah, AL-Furat AL-Awsat Technical University, Najaf, IQ
Source
Research Journal of Pharmacy and Technology, Vol 12, No 7 (2019), Pagination: 3547-3550Abstract
In the current study, seventy of patients who suffering of IHD and the control group was composed of 20 healthy. The samples were collected from the Coronary Care Unit (CCU) in Al-Sadder Teaching Hospital in Al-Najaf province/ Iraq, during the period from September till December 2018. The ages of patients and control ranged from 30 to 69 years old. The Patients groups are divided into subgroup according blood pressure and Body mass index. The results of current study revealed significant differences between IHD group and healthy group, significantly increased (p<0.05) in serum visfatin level and W.C., BMI compared with healthy group. The results indicated a significant increased (p<0.05) in serum VF level of hypertensive group compared with normotensive group in IHD patients. The results indicated when compared with different BMI (normal, over, obese and morbid weight) groups of IHD, there was a significant increase (p>0.05) in VF concentration among different BMI. The result indicated positive correlation between BMI, W.C.) and (VF). Conclusion: The current study concluded that visfatin level were good marker for detection and diagnosis of ischemic heart disease, and visfatin highly related with risk factors of ischemic heart disease such as hypertensive blood pressure and obesity.Keywords
Ischemic Heart Disease, Visfatin , Obesity and Hypertension.References
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