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Larichev, V. F.
- Effects of L-lysine-α-Oxidase from Trichoderma In Vitro Experiments on the model of Viruses as Sindbis, Tick-Borne encephalitis, West Nile, Tahyna and Dhori
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Authors
V. F. Larichev
1,
I. P. Smirnova
2,
S. P. Syatkin
2,
G. I. Myandina
2,
S. M. Chibisov
2,
Е. А. Ryskina
2
Affiliations
1 Federal State Budgetary Institution “Research Institute of Epidemiology and Microbiology Named after Honorable Academician N. F. Gamaleya”, 16 Gamalei Str, Moscow, RU
2 Medical Department of Medical Institute of Peoples’ Friendship University of Russia, 3 Ordzhonikidze Str., Moscow, RU
1 Federal State Budgetary Institution “Research Institute of Epidemiology and Microbiology Named after Honorable Academician N. F. Gamaleya”, 16 Gamalei Str, Moscow, RU
2 Medical Department of Medical Institute of Peoples’ Friendship University of Russia, 3 Ordzhonikidze Str., Moscow, RU
Source
Research Journal of Pharmacy and Technology, Vol 10, No 3 (2017), Pagination: 765-768Abstract
For the first time we studied the effect of the anticancer drug L-lysine-α-oxidase, obtained from culture liquid of Trichoderma harzianum Rifai F-180.
In vitro experiments we established the high activity of L-lysine-α-oxidase in a model of tick-borne encephalitis and the lack of activity against viruses Sindbis, West Nile, Tahyna and Dhori.