Research Journal of Pharmacy and Technology

Sisira Padavala ¹, P. Gopinath ²

Affiliations
1 Saveetha Dental College, Saveetha University, Chennai, IN
2 Department of Microbiology, Saveetha Dental College, Saveetha University, Chennai, IN

Abstract

Esp gene is a high molecular weight surface protein whose frequency is significantly increased among infection derived Enterococcus faecalis isolates. Esp gene is an Enterococcal surface protein gene which is present in the opportunistic pathogens Enterococcus faecalis and Enterococcus faecium. It has been proposed that esp gene can be used as a marker of human pollution in environmental waters. This gene has been shown to be a part of a 150-in putative pathogenicity island. A sum of 20 isolates of Enterococci were assessed for the presence of esp gene that encodes for extracellular surface protein. We have observed 5% positivity in our study. This indicates that, the pathogenicity of urinary tract infections by these pathogens might be crucially played by this gene encoding for extra cellular surface protein.

Keywords

Enterococcus faecalis, Esp Gene, PCR.

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Sisira Padavala ¹, M. G. Aarthy ²

Affiliations
1 Saveetha Dental College, Saveetha University, Chennai, IN
2 Department of Conservative Dentistry and Endodontics, Saveetha Dental College, Saveetha University, Chennai, IN

Abstract

Root perforations are artificial connections between the ischolar_main canal system and the periodontium and/or the oral cavity. They are undesired complications of endodontic treatment. It is very important to seal the site of perforation once diagnosed to minimize injury and prevent contamination of the surrounding periodontal attachment apparatus. Mineral trioxide aggregate is an endodontic cement used in treatment of ischolar_main perforations and it is extremely biocompatible, hydrophilic and capable of stimulating the healing processes. Root perforation is a sign of endodontic failure and is the most common complication of endodontic therapy. The aim of this review is to understand the effectiveness of MTA in management of ischolar_main perforations and to determine the prognosis of the treatment. Knowing the effectiveness of MTA may fasten the treatment and be more effective compared to other methods.

Keywords

MTA, Root Perforation.

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