Refine your search
Collections
Co-Authors
Year
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Radha, R.
- Review article on Luffa acutangula (L) Roxb
Abstract Views :158 |
PDF Views:0
Authors
Affiliations
1 Department of Pharmacognosy, Madras Medical College, Chennai, IN
1 Department of Pharmacognosy, Madras Medical College, Chennai, IN
Source
Research Journal of Pharmacy and Technology, Vol 12, No 5 (2019), Pagination: 2553-2558Abstract
Luffa acutangula (L) Roxb (Family: Cucurbitaceae) is commonly known as Ridge gourd. It is a widely growing vegetative climber. This plant is valuable for antimicrobial, antioxidant, anti-inflammatory, analgesic, abortifacient, anti-tumour, antiulcer, antibacterial, ameliorative, antiproliferative, antiangiogenic, antidiabetic, cytotoxic, hepatoprotective, immunomodulatory and larvicidal effect. This present review is focused on the pharmacognostical characters like scientific classification, vernacular name, chemical constituents, nutritional value and the plant potential in biological activity. This review will be more useful for student further research.Keywords
Luffa acutangula, Phytochemistry, Pharmacology.
References
- Quality Standards of Indian Medicinal Plants, Vol 9, Indian Council of Medical Research. p. 218-232.
- Medicinal Plants of India, Dinesh Jadhav, Vol 1, p. 152-153.
- Ayurvedic Pharmacopoeia, Part I, 3, 150-153.
- Zhou et al. Thermotolerance of Luffa acutangula seedlings and their physiological response to heat stress. Journal of Tropical and Subtropical Botany 2017; 25(4):357-369.
- Siti Nurai’syah et al. Mechanical properties of High loading Luffa acutangula fiber with Cloisite 15A and polypropylene. Advanced materials research 2016; 1134:178-184.
- Hon Wei et al. Luffa acutangula peel as an effective natural biosorbent for malachite green removal in aqueous media: equilibrium, kinetic and thermodynamic investigations. Desalination and Water Treatment 2016; 57(16):7302-7311.
- Suryanti V, Marliyana SD, Astuti IY and Iop. Chemical constituents of Luffa acutangula (L.) Roxb fruit. International conference on Food Science and Engineering 2016; 193.
- Taruna et al. Green synthesis and physico-chemical study of silver nanoparticles extracted from a natural source Luffa acutangula. Journal of Molecular Lipids 2016; 224:991-998.
- Swetha MP and Muthukumar SP. Characterization of nutrients, amino acids, polyphenols and antioxidant activity of Ridge gourd (Luffa acutangula) peel. Journal of Food Science and Technology-Mysore 2016; 53(7):3122-3128.
- Vanajothi, Ramar and Srinivasan, Pappu. Bioassay guided isolation and identification of bioactive compound from aerial parts of Luffa acutangula against lung cancer cell line NCI-H460. Journal of Receptors and Signal Transduction 2015;35(4):295-302.
- Lin et al. Purification and Characterization of two Luffaculins, Ribosome-inactivating proteins from seeds of Luffa acutangula. Chinese Journal of Biochemistry and Molecular biology 2002; 18(5):609-613.
- Nagao T, Tanaka R and Okabe H. Studies on the constituents of Luffa acutangula Roxb.2.structures of acutoside-H and acutoside-I, Oleanolic acid saponins isolated from the seed. Chemical and Pharmaceutical Bulletin 1991; 39(4):889-893.
- Salma SH, Sabir AW and Khan SA. Cultivation conditions and physic-chemical properties of Luffa acutangula –var-acutangula seed oil. Pakistan Journal of Scientific and Industrial Research 1985; 28(2):119-122.
- Barua AK, Chakraborti, Sachindra K nad Ray, Asit Kumar. Chemical examination of the seeds of Luffa acutangula Roxb. Journal of the Indian Chemical Society 1958; 35(7):480-482.
- Singh et al. Heterosis for Quantitative traits and mineral contents in ridge gourd (Luffa acutangula). Indian Journal of Agricultural Sciences 2017; 87(3):379-384.
- Wang et al. Determination of elements in leaf of Luffa acutangula (L.) Roxb sing high-pressure microwave digestion and ICP-AES. Journal of Southern Agriculture 2012; 43(1):90-93.
- Torvi JR and Hunashal RD. A study on antimicrobial activity of extracts of Luffa acutangula var amara fruits. International Journal of Pharma and Bio-Sciences 2012; 3(4):678-685.
- Suryanti V, Marliyana SD and Wulandari T. Antioxidant activity, total phenolics and flavonoids contents of Luffa acutangula (L.) Roxb fruit. Journal of Chemical and Pharmaceutical Research 2015; 7(1):220-226.
- Ananthan, Padmashree, Sharma GK, Semwal AD and Bawa AS. In vitro antioxygenic activity of ridge gourd (Luffa acutangula) pulp, peel and their extracts on peroxidation models. Americal Journal of Plant Sciences 2012; 3(10):1413-1421.
- Reddy BP, Mohan SV and Sarma PN. The protective role of Luffa acutangula fruit methanolic fraction against t-BHP induced oxidative damage in human erythrocytes. Current trends in Biotechnology and Pharmacy 2011; 5(1):1073-1082.
- Gill NS, Rashmi, Arora and Kumar SR. Evaluation of antioxidant, anti-inflammatory and analgesic potential of the Luffa acutangula Roxb var amara. Research Journal of Phytochemistry 2011; 5(4):201-208.
- Fernandes LCB, Cordeiro LAV and Soto-Blanco B. Evaluation of the abortifacient effect of Luffa acutangula Roxb in rats. p. 270-273.
- Dashora N and Chauhan LS. In vitro antioxidant and in vivo anti-tumour activity of Luffa acutangula against Dalton’s Lymphoma ascites (DLA) cells bearing mice. Journal of Chemical and Pharmaceutical Research 2015; 7(6):940-945.
- Pimple BP, Kadam PV and Patil MJ. Protective effect of Luffa acutangula extracts on gastric ulceration in NIDDM rats: Role of gastric mucosal glycoproteins and antioxidants. Asian Pacific Journal of Tropical Medicine 2012; 5(8):610-615.
- Mustarichie R, Udin LZ, Muchtaridi and Supriyatna. Identification and antbacterial activity of methanol extract of Luffa acutangula Roxb. Medical and Health Sciences Journal 2012; 12:70-77.
- Jadhav, Vishal B, Thakare, Vishnu N, Suralkar, Anupama A and Naik, Suresh R. Ameliorative effect of Luffa acutangula Roxb on Doxorubicin induced cardiac and nephrotoxicity in mice. Indian Journal of Experimental Biology 2013; 51(2):149-156.
- Reddy BP, Goud RK, Mohan SV and Sarma PN. Antiproliferative and antiangiogenic effects of partially purified Luffa acutangula fruit extracts on human lung adenocarcinoma epithelial cell line (A-549). Current trends in Biotechnology and Pharmacy 2009; 3(4):396-404.
- Pimple BP, Kadam PV and Patil J. Antidiabetic and antihyperlipidemic activity of Luffa acutangula fruit extracts in streptozotocin induced NIDDM rats. Asian Journal of Pharmaceutical and Clinical Research 2011; 4(2):156-163.
- Nipun, Dashora, Chauhan LS and Neeraj, Kumar. In vitro cytotoxic activity of Luffa acutangula on human neuronal glioblastoma and human lung adenocarcinoma cell lines. Scholars Academic Journal of Pharmacy 2014; 3(5):401-405.
- Mishra, Shanthi Bhushan and Mukerjee, Alok. In vivo and ex vivo evaluation of Luffa acutangula fruit extract and its fractions for hepatoprotective activity in wistar rats. International Journal of Pharmaceutical Sciences and Research 2017; 8(12):5227-5233.
- Gupta KA, Rizvi W, Kumar A and Khan AA. Hepatoprotective effect of seeds of Luffa acutangula in carbon tetrachloride induced hepatotoxicity in rats. Indian Journal of Pharmacology 2013; 45:S175-S176.
- Ulaganathan I, Divya D, Radha K, Vijayakumar TM and Dhanaraju MD. Protective effect of Luffa acutangula (var) amara against carbon tetrachloride induced hepatotoxicity in experimental rats. Research Journal of Biological Sciences 2010; 5(9):615-624.
- Jadhav et al. Hepatoprotective activity of Luffa acutangula against carbon tetrachloride and rifampicin induced liver toxicity in rats: A biochemical and histopathological evaluation. Indian Journal of Experimental Biology 2010; 48(8):822-829.
- Mohan, Kalaskar G and Sanjay, Surana J. Free radical scavenging, immunomodulatoryand chemical composition of Luffa acutangula var amara pericarp. Journal of the Chilean Chemical Society 2014; 5(1):2299-2302.
- Mullai K, Jebanesan A nad Pushpanathan T. Bioactivity of the leaf extract of Luffa acutangula Roxb against the mosquito Aedes egypti (L). Journal of Experimental Zoology India 2007; 10(1):165-167.
- Arunachalam A, Selvakumar S and Jeganath S. Toxicological studies on ethanol extract of iLuffa acutangula in albino wistar rats. International Journal of Current Pharmaceutical and Clinical Research 2012; 2(1):29-33.
- Colon Targeted Drug Delivery System of Phytoconstituents
Abstract Views :424 |
PDF Views:0
Authors
Affiliations
1 Department of Pharmacognosy, Madras Medical College, Chennai, IN
1 Department of Pharmacognosy, Madras Medical College, Chennai, IN
Source
Research Journal of Pharmacy and Technology, Vol 12, No 7 (2019), Pagination: 3144-3150Abstract
Now a day’s world health organization encourage, recommends and promotes traditional, herbal remedies in health care sciences, because these drugs low in cost, easily available and are safe. The main advantage of using phytoconstituents is free from adverse effects where none of the medication can do. However, the physiochemical properties such as poor permeation, poor solubility and non- targeting at the active site creates a barriers which hinders its therapeutic efficacy. So, targeted drug delivery strategies are employed to overcome these barriers and provide uniform drug targeting at the active site in desired concentration and improved therapeutic efficacy. These day’s colonic diseases are commonly seen and needs lifelong medical attention. Herbal medicines can play vital role in the treatment of colonic diseases like ulcerative colitis, intestinal bowel syndrome, colon cancer and Crohn’s disease. This review article discusses in brief, introduction to targeted drug delivery, factors influence the drug targeting and approaches for enhancing the therapeutic potential of phytoconstituents having wide biological activities.Keywords
Colon Drug Delivery, Factors, Approach, Phytoconstituents.References
- Anya M. Hillery, Andrew W. Lioyd, James Swarbrick. The Textbook of Drug Delivery and Targeting for Pharmacists and Pharmaceutical Scientists. Special Indian Edition., New Delhi; CRC press: 2010.
- Sardarmal Yadav, Ashish Kumar Pareek, Dr. Shiv Garg, Manoj Kumar and Pradeep Kumar. Recent Advances In Colon Specific Drug Delivery System. World Journal of Pharmaceutical Sciences 2015; 4(6): 1380-1394.
- Nishant Singh and Dr. R.. C. Khanna. Colon Targeted Drug Delivery Systems- A Potential Approach Pharmaceutical Research. The Pharma Inoovation 2012; 1(2): 3120-3132.
- Bhushan Prabhakar Kolte, Kalyani V. Tele, Vinayak S. Mundhe, Sandeep S. Lahoti. Colon Targeted Drug Delivery System- A Novel Perspective. Asian Journal of Biomedical and Pharmacutical Sciences 2012.
- Kushaldhir, Harminderpal Singh Kahlon and Sukhbirkaur. Recent Approaches For Colon Targeted Drug Delivery System. International Journal of Pharmaceutical, Chemical and Biological Sciences 2013; 3(2): 360-371.
- Surender Verma, Vipin Kumar, D. N. Mishra and S. K. Singh. Colon Targeted Drug Delivery: Current And Novel Perspectives. International Journal of Pharmaceutical Sciences and Research 2012; 3(5): 1274-1284.
- Pawar Dhanashree G, Darekar Avinash B, Saudagar Ravindra B. Colon Targeted Drug Delivery System: Pharmaceutical Approaches With Current Trends. World Journal of Pharmacy and Pharmaceutical Sciences 2013; 2(6): 6589-6612.
- Trishna Debnath, Da Hye Kim and Beong Ou Lim. Natural Products as a Source of Antiinflammatory Agents Associated with Inflammatory Bowel Disease. Molecules 2013; 18: 7253-7270.
- Subapriya Rajamanickam and Rajesh Agarwal. Natural Products and Colon Cancer: Currrent Status and Future Prospects. NIH Public Access 2008; 69(7): 460-471.
- Pratik Terse and Rashmi Mallya. Importance of Colon Targeted Drug Delivery System in Herbal Medicines. International Journal of Pharmaceutical Sciences and Research 2017; 8(11): 4513-4524.
- Jasvir Kaurl. Geeta Aggarwal, Anu Maharajan and Satvinder Kaur. Colon Targeted Drug Delivery System To Treat Colorectal cancer. World Journal of Pharmacy and Pharmaceutical Science 2015; 5(01): 407-420.
- Anil Bhandari, Imran Khan Pathan, Peeyush K. Sharma, Rakesh K. Patel, Suresh Purohit. Development and Optimization of Colon Taregeted Drug Delivery System of Ayurvedic Churna Formulation Using Eudragit L100 and Ethly Cellulose As Coating Material. International Journal of Pharmacological and Pharmaceutical Sciences 2013.
- Mundhe Vinayak S, Dodiya Shamsundar S. Review Article: Novel Approach for Colon Targeted Drug Delivery. Indo American Journal of Pharmaceutical Research 2011: 3: 158-173.
- Suresh kumar R, Ganesh GN, Jawahar N, Nagasamy Venkatesh D, Senthil V, Raju l and Samantha M. Formulation and Evaluation of pectin-hydroxy propyl methyl cellulose coated curcumin pellets for colon delivery. Asian Journal of Pharmaceutics 2009; 3(2): 138.
- Danda Sreelatha and Chandan Kumar Brahma. Colon Targeted Delivery – A review on Primary and Novel Approaches. Journal of Global Trends in Pharmaceutical Science 2013; 4(3): 1174-1183.
- Ravi Kumar, M. B. Patil, Sachin R. Patil, Mahesh S. Paschapur. Polysaccharides Based Colon Specific Drug Delivery: A Review. International Journal of Pharm Tech Research 2009; 1(2): 334-346.
- Ahuja Naresh and Bhandari Anil, Devendra Yadav, Atul Garg and Sanjay Khanna. Formulation and Development of Controlled Release Multiparticulate Tabltes Using Blends of Various Natural Gum. International Journal of Research in Pharmacy and Chemistry 2012; 2(3): 2231-2781.
- S. P. Vyas. Theory and Practice in Novel Drug Delivery System. First Edition, India binding house; Noida: 2009.
- Nitin B. Charbe, Paul A. McCarron, Majella E. Lane, Murtaza M. Tambuwala. Application of Three-Dimensional Printing For Colon Targeted Drug Delivery Systems. International Journal of Pharmaceutical Investigation 2017; 7: 47-59.
- Vinay K Gupta, G.Gnanarajan, Preeti Kothiyal. A Review Article on Colonic Targeted Drug Delivery System. The Pharma Innovation 2012; 1(7): 2277-7695.
- Huang Y, Tian R, Hu W, Jia Y, Zhang J, Jiang H and Zhang L: A Novel Plug-Controlled Colon-Specific Pulsatile Capsule With Tablet of Curcumin-Loaded SMEDDS. Carbohydrate Polymers 2013; 92(2): 2218-23.
- R.B. Desi Reddy, K. Malleswari, G. Prasad and G. Pavani. Colon Targeted Drug Delivery System: A Review. International Journal of Pharmaceutical Sciences and Research 2012; 4(1): 42-54.
- Hang M, Viennois E, Prasad M, Zhang Y, Wang L, Zhang Z, Han MK, Xiao B, Xu C, Srinivasan S and Merlin D. Edible Ginger-Derived Nanoparticles: A Novel Therapeutic Approach For The Prevention and Treatment of Inflammatory Bowel Disease and Colitis-Associated Cancer. Biomaterials 2016; 1(01): 321-400.
- Ankit Vajpayee, Suresh Fartyal, Alok Pratap Singh, Sajal Kumar Jha. Formulation and Evaluation of Colon Targeted and Opnion 2011; 1(4): 108-112.
- Madhavi M, Madhavi K and Jithan AV: Preparation and in vitro/in vivo Characterization of Curcumin Microspheres Intended to Treat Colon Cancer. Journal of Pharmacy and Bioallied Science 2012; 4(2): 164.