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The Effect of Guidance regarding Home Exercise and ADL on Adolescent Females Suffering from Adverse Effects after HPV Vaccination in Japanese Multidisciplinary Pain Centers


Affiliations
1 Multidisciplinary Pain Centre, School of Medicine, Aichi Medical University, Aichi 480-1195, Japan
2 Department of Pain Medicine, Osaka University, Graduate School of Medicine, Japan
3 Pain Clinic,The Jikei University Hospital, Japan
4 Department of Orthopedic Surgery, Fukushima Medical University School of Medicine, Japan
5 Department of Pain and Palliative Medicine,The University of Tokyo Hospital, Japan
6 Department of Rehabilitation Medicine, Sapporo Medical University, Japan
7 Department of Anesthesiology and Pain Management, Juntendo University School of Medicine, Japan
8 Department of Psychosomatic Medicine, Kyushu University Hospital, Japan
9 Department of Anesthesiology & Critical Care Medicine, Kyushu University Hospital, Japan
10 Department of Orthopedic Surgery, Okayama University Hospital, Japan
11 Department of Anesthesiology and Resuscitology, Okayama University Hospital, Japan
12 Interdisciplinary Pain Management Center, Shiga University of Medical Science Hospital, Japan
13 Department of Orthopedic Surgery, Kochi Medical School, Japan
 

Background: Two prophylactic papillomavirus (HPV) vaccines have been available for primary prevention of cervical cancer. Although serious adverse effects (AE) were rare, more than 230 women have been suffering from severe AEs such as persistent pain and headache in Japan. Our research group started to treat adolescent females suffering from the AEs. Objective: To survey the characteristics of and the effects of cognitive behavioral therapy on adolescent female suffering from the AEs in Japanese multidisciplinary pain centers. Methods: One hundred and forty-five patients suffering fromthe AEs were reviewed retrospectively and 105 patients of them were provided guidance on home exercise and activities of daily living based partially on a cognitivebehavioral approach.The intensity of pain was rated by the patients using a numerical rating scale (NRS). Furthermore, theHospital Anxiety and Depression Scale (HADS) and the Pain Catastrophizing Scale (PCS) were used. Results: Eighty out of the 105 patients who received the guidance were followed up, 10 displayed amarked improvement, and 43 showed some improvement. Conclusions: Guidance on home exercise and activities of daily living based on a cognitive-behavioral approach alleviated the AEs that women suffered from after HPV vaccination in Japan.
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  • The Effect of Guidance regarding Home Exercise and ADL on Adolescent Females Suffering from Adverse Effects after HPV Vaccination in Japanese Multidisciplinary Pain Centers

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Authors

Takahiro Ushida
Multidisciplinary Pain Centre, School of Medicine, Aichi Medical University, Aichi 480-1195, Japan
Masahiko Shibata
Department of Pain Medicine, Osaka University, Graduate School of Medicine, Japan
Masaki Kitahara
Pain Clinic,The Jikei University Hospital, Japan
Shoji Yabuki
Department of Orthopedic Surgery, Fukushima Medical University School of Medicine, Japan
Masahiko Sumitani
Department of Pain and Palliative Medicine,The University of Tokyo Hospital, Japan
Takanori Murakami
Department of Rehabilitation Medicine, Sapporo Medical University, Japan
Masako Iseki
Department of Anesthesiology and Pain Management, Juntendo University School of Medicine, Japan
Masako Hosoi
Department of Psychosomatic Medicine, Kyushu University Hospital, Japan
Hiroaki Shiokawa
Department of Anesthesiology & Critical Care Medicine, Kyushu University Hospital, Japan
Tomoko Tetsunaga
Department of Orthopedic Surgery, Okayama University Hospital, Japan
Hiroyuki Nishie
Department of Anesthesiology and Resuscitology, Okayama University Hospital, Japan
Sei Fukui
Interdisciplinary Pain Management Center, Shiga University of Medical Science Hospital, Japan
Motohiro Kawasaki
Department of Orthopedic Surgery, Kochi Medical School, Japan
Sinsuke Inoue
Multidisciplinary Pain Centre, School of Medicine, Aichi Medical University, Aichi 480-1195, Japan
Makoto Nishihara
Multidisciplinary Pain Centre, School of Medicine, Aichi Medical University, Aichi 480-1195, Japan
Shuichi Aono
Multidisciplinary Pain Centre, School of Medicine, Aichi Medical University, Aichi 480-1195, Japan
Tatunori Ikemoto
Multidisciplinary Pain Centre, School of Medicine, Aichi Medical University, Aichi 480-1195, Japan
Takashi Kawai
Multidisciplinary Pain Centre, School of Medicine, Aichi Medical University, Aichi 480-1195, Japan
Young-Chang Arai
Multidisciplinary Pain Centre, School of Medicine, Aichi Medical University, Aichi 480-1195, Japan

Abstract


Background: Two prophylactic papillomavirus (HPV) vaccines have been available for primary prevention of cervical cancer. Although serious adverse effects (AE) were rare, more than 230 women have been suffering from severe AEs such as persistent pain and headache in Japan. Our research group started to treat adolescent females suffering from the AEs. Objective: To survey the characteristics of and the effects of cognitive behavioral therapy on adolescent female suffering from the AEs in Japanese multidisciplinary pain centers. Methods: One hundred and forty-five patients suffering fromthe AEs were reviewed retrospectively and 105 patients of them were provided guidance on home exercise and activities of daily living based partially on a cognitivebehavioral approach.The intensity of pain was rated by the patients using a numerical rating scale (NRS). Furthermore, theHospital Anxiety and Depression Scale (HADS) and the Pain Catastrophizing Scale (PCS) were used. Results: Eighty out of the 105 patients who received the guidance were followed up, 10 displayed amarked improvement, and 43 showed some improvement. Conclusions: Guidance on home exercise and activities of daily living based on a cognitive-behavioral approach alleviated the AEs that women suffered from after HPV vaccination in Japan.