Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Down Syndrome: a Literature Review


Affiliations
1 Department of Pedodontics and Preventive Children Dentistry, A.B Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India
2 Department of Pedodontics and Preventive Children Dentistry, AECS Maaruti dental college, Bangalore, Karnataka, India
3 Department of Pedodontics and Preventive Children Dentistry, A.B Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India
     

   Subscribe/Renew Journal


Down Syndrome (DS) is a genetic condition caused by a chromosomal abnormality and results in a characteristic appearance, learning disability and a variety of physical and medical features. . In India frequency of that occurrence is 2.2 per 1000 live births. Maternal age plays an important role in the frequency of Down syndrome. A wide variety of systemic (cardiovascular, hematopoietic, musculoskeletal, nervous) and oral anomalies (palate, oral opening, tongue, dental, periodontal and occlusion) are seen in Down syndrome children. Each individual may carry only limited anomalies which vary in its degree of severity and with age. These children require medical consultation and dentists do not need special skills or equipment to treat Down syndrome patients routinely in a dental office.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Arapostathis K.N, Konstantinidis A. Periodontal conditions and subgingival microflora in Downs Syndrome patients. A case- control study. Journal of Clinical Periodontology 2005; 32:684-690.
  • Pueschel.S et al. A historical viewpoint: Downs syndrome growing and learning. Downs syndrome (Human potential for children series) 1981; 37-39.
  • SeguinE. LeTraitement moral, I’hygiene et I’education des. J.B. Bailliere, Paris, 1846.
  • Langdon Down J. Observations on an ethnic classification of idiots. Clin Lect Rep London Hospital 1866; 3:249.
  • Lejuene J. Le mongolisme: Premier exemple d’aberretion autosomique humaine. Ann Genet 1959; 1:41-49.
  • Korenberg JR., Pulst SM., Gerwehrs. Advances in the understanding of chromosome 21 and Down Syndrome. In: Lott I, McCoy E, editors. Down syndrome: Advances in medical care. New York: Wiley-Liss; 1992. p. 3-12.
  • Grouchy J, de Turleau C. Autosomal disorders in principles and practise of Medical Genetics, Emery EH, Rimoin DL (eds), Churchill Livingstone, Edinburgh, 1983; 170-192.
  • Regezi J., Sciubba J. Oral pathology Clinical Pathologic Correlations. First Ed. In: Regezi, Sciubba, editors. Philadelphia: W.B. Saunders Co: 1989. p. 450-51.
  • Smith W.B. Recognizable Pattern of Human Malformations. Fourth ed. Jones LK, ed. Philadelphia: W.B. Saunders Co; 1988. p. 10-12.
  • P.L. Kaye, J. Fiske, E. J. Bower, J. T. Newton and M. Fenlon. Views and experiences of parents and siblings of adults with Down Syndrome regarding oral healthcare: a qualitative and quantitative study. British Dental Journal 2005; 198:571-578.
  • Rebecca B. Saenz. Primary Care of Infants and Young Children with Down Syndrome. American Family Physician 1999; 59(2):392-5.
  • Sindoor S. Desai. Down Syndrome: A Review of the Literature. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics 1997; 84:279-85.
  • Stark A. Dentistry: Down syndrome advances in biomedicine and behavioral sciences. In: Pueschel, Rynders. editors. Cambridge, MA: 1982. p. 198- 203.
  • Garn SM., Cohen M., Gall JC., Nagy J. Relative magnitudes of crown size reduction and body size. J Dent Res.1971; 50:513.
  • Scully C. Down syndrome: aspects of dental Care. J. of Dent 1976; 4:167-74.
  • Sterling ES. Oral and dental considerations in Down syndrome. In: Lott I, McCoy E, editors. Down syndrome: Advances in medical care. New York: Wiley-Liss; 1992: p. 135-45.
  • Jaspers M. Taurodontism in the Down syndrome. Oral Surg Oral Med, Oral Pathol. Jun.1981; 51: 632-636.
  • Ibsen O., Phelan J. Developmental disorders. Oral pathology for dental hygienist. Philadelphia: WB Saunders Co; 1996. p. 246-47.
  • Townsend GC. Dental crown variants in children and young adults with Down syndrome. Act Odontol Pediat. Dec. 1986; 7:35-9.
  • Russell BG., Kjær I. Tooth agenesis in Down syndrome. Am J Med Genet 1995; 55:466-71.
  • Orner G. Dental caries experience among children with Down syndrome and their sibs. Arch Oral Bio. 1975; 20:627-34.
  • Shapira J., Stabholz A., Schurr D., Sela M., Mann J. Caries levels, Streptococcus mutant counts, salivary pH and periodontal treatment needs of adult Down syndrome patients. Special Care Dentistry. 1991; 11:248-51.
  • Chan AR. Dental caries and periodontal disease in Down’s syndrome patients. Univ. Toronto Dent J.1994; 7:18-20
  • Ondaraza AJL., Blanco R., Valenzuela C. The sequence of eruption of permanent dentition in a Chilean sample with Down syndrome. Arch Biol 1993; 38:85-9.
  • Shaw L., Saxby MS. Periodontal destruction in Down syndrome and in juvenile periodontitis: How close a similarity? J. Periodontal. 1986; 57:709-13.
  • Nowak A. Primary preventive dentistry for children. Update in Ped Dent 1990; 13:1-6.
  • Fardal O., Turnbull RS. A review of literature on the use of chlorhexidinein dentistry. J Am Dent Assoc 1986; 112:863-9.
  • Ondarza AJL., Bertonati MI., Blanco R. Tooth malalignments in Chilean children with Down syndrome. Cleft Palate-Craniofac J 1995; 32: 188-193.
  • Borea G., Magi M., Mingarelli R., Zamboni C. The oral cavity in Down syndrome. J of Pedodontics 1990; 14:139-140.
  • Sassouni V., Forrest E. Dentofacial pathology related to malocclusion. Orthodontics in Dental Practice. St. Louis: MO. Mosby; 1971. p. 169-197.

Abstract Views: 1187

PDF Views: 2




  • Down Syndrome: a Literature Review

Abstract Views: 1187  |  PDF Views: 2

Authors

Shilpa K Shetty
Department of Pedodontics and Preventive Children Dentistry, A.B Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India
Nischitha Naik
Department of Pedodontics and Preventive Children Dentistry, A.B Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India
K N Pradeep Kumar
Department of Pedodontics and Preventive Children Dentistry, AECS Maaruti dental college, Bangalore, Karnataka, India
Amitha M Hegde
Department of Pedodontics and Preventive Children Dentistry, A.B Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India

Abstract


Down Syndrome (DS) is a genetic condition caused by a chromosomal abnormality and results in a characteristic appearance, learning disability and a variety of physical and medical features. . In India frequency of that occurrence is 2.2 per 1000 live births. Maternal age plays an important role in the frequency of Down syndrome. A wide variety of systemic (cardiovascular, hematopoietic, musculoskeletal, nervous) and oral anomalies (palate, oral opening, tongue, dental, periodontal and occlusion) are seen in Down syndrome children. Each individual may carry only limited anomalies which vary in its degree of severity and with age. These children require medical consultation and dentists do not need special skills or equipment to treat Down syndrome patients routinely in a dental office.

References