Journal of Pierre Fauchard Academy (India Section)

Axita C. Dedhia ¹, Ramniwas M. Kumawat ², Priyanka S. Kadoo ³, Vishal D. Solanke ⁴, Ravi Tale ⁵, Neeta Bokade ⁶

Affiliations
1 Department of Oral Pathology, Govt. Dental College and Hospital, Mumbai, Maharashtra, IN
2 Department of Oral Pathology and Microbiology, Center for Dental Education and Research (AIIMS), New Delhi, IN
3 Department of Oral Pathology and Microbiology, SDKS Dental College and Hospital, Nagpur, Maharashtra, IN
4 Department of Oral Pathology and Microbiology, Dr. HSRSM's Dental College and Hospital, Hingoli, Maharashtra, IN
5 Department of Oral Pathology and Microbiology, Saraswati-Dhanwantari Dental College and Hospital, Parbhani, Maharashtra, IN
6 Ministry of Health, BH

Abstract

Pemphigus vulgaris (PV) is an autoimmune blistering disease characterized by circulating pathogenic IgG autoantibodies against desmoglein 3 and desmoglein 1. Oral lesions readily rupture, new bullae developing as the older ones rupture and ulcerate. Oral lesions may precede cutaneous lesions in 53.52% cases. Prompt recognition and diagnosis is critical since it may prevent cutaneous involvement. Systemic steroids remain the gold standard treatment of PV. Their use has transformed what was almost invariably a fatal illness into one whose mortality is now below 10%. We report a case of patient with oral ulcers since 4 months, who is diagnosed with PV without cutaneous involvement.

Keywords

Corticosteroids, Mucous Membrane, Oral Ulcer, Pemphigus Vulgaris.

Full Text