Journal of Pierre Fauchard Academy (India Section)

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Oral Pemphigus Vulgaris with Cutaneous Manifestations: A Case Report


Affiliations
1 Department of Periodontology and Oral Implantology, Desh Bhagat Dental College, Gobindgarh -147301, Punjab, India
2 Department of Oral Pathology and Microbiology, Manav Rachna Dental College, Faridabad – 121001, Haryana, India
     

   Subscribe/Renew Journal


Pemphigus is a life threatening mucocutaneous disease characterized by production of auto-antibodies against desmosomal glycoproteins. This results in the formation of intra epithelial blisters. The etiology of this disease remains obscure, although the presence of autoantibodies confirms autoimmune origin. The initial manifestation is frequently the development of intraoral lesions, and later, may involve other mucous membranes and skin. As oral lesions are first to appear, dental professionals must be well acquainted with the clinical presentation of pemphigus vulgaris to ensure timely diagnosis and appropriate treatment. In this article, we report a case of 54- year-old male, who was diagnosed with pemphigus vulgaris.


Keywords

Dental Professionals, Oral Manifestations, Pemphigus Vulgaris, Tzanck Cells.
User
Subscription Login to verify subscription
Notifications
Font Size

  • Grando SA. Pemphigus autoimmunity: Hypotheses and realities. Autoimmunity. 2012; 45:7–35. https://doi.org/10.3109/08916934.2011.606444. PMid:21939410. PMCid:PMC3251002

  • Rajendran R. Diseases of skin. Shafer's Textbook of Oral Pathology. 6th ed. Rajendran R, Sivapathasundaram B, editors, Philadelphia: Elsevier; 2009. p. 797-843.

  • Shamim T, Varghese VZ, Shameena PM, Suddha S. Pemphigus Vulgaris in oral cavity. Clinical analyses of 71 cases. Med Oral Pathol Buccal. 2008; 13:2622–26226.

  • Fellner MJ, Sapadin AN. Current therapy of pemphigus vulgaris. Mt Sinai J Med. 2001; 68(4–5):268–278.

  • Toth GG, Jonkman MF. Therapy of pemphigus. Clin Dermatol. 2001; 19(6):761–767 https://doi.org/10.1016/S0738-081X(00)00190-5


Abstract Views: 244

PDF Views: 0




  • Oral Pemphigus Vulgaris with Cutaneous Manifestations: A Case Report

Abstract Views: 244  |  PDF Views: 0

Authors

Jaspreet Singh Gill
Department of Periodontology and Oral Implantology, Desh Bhagat Dental College, Gobindgarh -147301, Punjab, India
Sharanjeet Gill
Department of Oral Pathology and Microbiology, Manav Rachna Dental College, Faridabad – 121001, Haryana, India

Abstract


Pemphigus is a life threatening mucocutaneous disease characterized by production of auto-antibodies against desmosomal glycoproteins. This results in the formation of intra epithelial blisters. The etiology of this disease remains obscure, although the presence of autoantibodies confirms autoimmune origin. The initial manifestation is frequently the development of intraoral lesions, and later, may involve other mucous membranes and skin. As oral lesions are first to appear, dental professionals must be well acquainted with the clinical presentation of pemphigus vulgaris to ensure timely diagnosis and appropriate treatment. In this article, we report a case of 54- year-old male, who was diagnosed with pemphigus vulgaris.


Keywords


Dental Professionals, Oral Manifestations, Pemphigus Vulgaris, Tzanck Cells.

References





DOI: https://doi.org/10.18311/jpfa%2F2019%2F22337