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Comparative Evaluation of Tissue Dissolution Efficacy of Azadirachta indica Irrigant and Sodium Hypochlorite – An in vitro Study


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1 Department of Conservative Dentistry and Endodontics, Vishnu Dental College, Vishnupur, Bhimavaram, West Godavari District - 534202, Andhra Pradesh, India
2 Department of Conservative Dentistry and Endodontics, Vishnu Dental College, Vishnupur, Bhimavaram, West Godavari District - 534202, Andhra Pradesh
     

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Objectives: This study aimed to evaluate the tissue dissolution efficacy of Azadirachta indica (A. indica) irrigant and sodium hypochlorite. Materials and Methods: 40 bovine muscle tissue specimens of equal dimensions were used in the experiment. Based on tissue specimen treatment, they were divided into four test groups - 3%NaOCl (Group I), 7.5% A. indica irrigant (Group II), alternative use of 3%NaOCl and 7.5% A. indica irrigant (Group III) and control group as distilled water (Group IV). Tissue specimens were weighed before and after placing in test solutions at 2 different time intervals (30,60 minutes). Results: The results revealed that 3%NaOCl showed highest tissue dissolution followed by alternative use of 3%NaOCl. and A. indica irrigant, A. indica alone and distilled water (Group I >III>II>IV). The larger the duration of contact with irrigant better is the tissue dissolution. Conclusion: 7.5% A. indica irrigant alone does not have any tissue dissolving property but in combination it acts as a neutral solution neither increasing nor decreasing the capability of 3%NaOCl.

Keywords

Azadirachta indica, NaOCl, Smear Layer, Tissue Dissolution
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  • Comparative Evaluation of Tissue Dissolution Efficacy of Azadirachta indica Irrigant and Sodium Hypochlorite – An in vitro Study

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Authors

Girija S. Sajjan
Department of Conservative Dentistry and Endodontics, Vishnu Dental College, Vishnupur, Bhimavaram, West Godavari District - 534202, Andhra Pradesh, India
Podugu Uday Kumar
Department of Conservative Dentistry and Endodontics, Vishnu Dental College, Vishnupur, Bhimavaram, West Godavari District - 534202, Andhra Pradesh, India
T. Rambabu
Department of Conservative Dentistry and Endodontics, Vishnu Dental College, Vishnupur, Bhimavaram, West Godavari District - 534202, Andhra Pradesh, India
K. Madhu Varma
Department of Conservative Dentistry and Endodontics, Vishnu Dental College, Vishnupur, Bhimavaram, West Godavari District - 534202, Andhra Pradesh, India
R. Kalyan Satish
Department of Conservative Dentistry and Endodontics, Vishnu Dental College, Vishnupur, Bhimavaram, West Godavari District - 534202, Andhra Pradesh
G. Prasanthi
Department of Conservative Dentistry and Endodontics, Vishnu Dental College, Vishnupur, Bhimavaram, West Godavari District - 534202, Andhra Pradesh, India

Abstract


Objectives: This study aimed to evaluate the tissue dissolution efficacy of Azadirachta indica (A. indica) irrigant and sodium hypochlorite. Materials and Methods: 40 bovine muscle tissue specimens of equal dimensions were used in the experiment. Based on tissue specimen treatment, they were divided into four test groups - 3%NaOCl (Group I), 7.5% A. indica irrigant (Group II), alternative use of 3%NaOCl and 7.5% A. indica irrigant (Group III) and control group as distilled water (Group IV). Tissue specimens were weighed before and after placing in test solutions at 2 different time intervals (30,60 minutes). Results: The results revealed that 3%NaOCl showed highest tissue dissolution followed by alternative use of 3%NaOCl. and A. indica irrigant, A. indica alone and distilled water (Group I >III>II>IV). The larger the duration of contact with irrigant better is the tissue dissolution. Conclusion: 7.5% A. indica irrigant alone does not have any tissue dissolving property but in combination it acts as a neutral solution neither increasing nor decreasing the capability of 3%NaOCl.

Keywords


Azadirachta indica, NaOCl, Smear Layer, Tissue Dissolution

References





DOI: https://doi.org/10.18311/jpfa%2F2018%2F22121