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Shanmuga Priya, G.
- Antibacterial and in vitro Anticancer Study of Methanol Extracts of Clitoria ternatea Leaves
Abstract Views :308 |
PDF Views:401
Authors
Arunava Das
1,
G. Shanmuga Priya
1,
S. Soundariya
1,
P. Deepesh
1,
Aileen Rose Edwin
1,
E. Vihashinee
1,
A. Rubiga
1,
S. Megavarthini
1,
R. Eswaran
1,
J. Bindhu
1
Affiliations
1 Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode, IN
1 Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode, IN
Source
Journal of Natural Remedies, Vol 20, No 2 (2020), Pagination: 96-102Abstract
Clitoria ternatea is often known as butterfly pea plant by the natives and is one of the major plants used in Ayurveda and traditional medicine worldwide. It is also used in food and cosmetic industries for various purposes. In this study, methanol leaf extract of Clitoria ternatea was studied for its antibacterial and in vitro anticancer study against human promyelocytic leukemia cells (HL60). Secondary metabolites like alkaloids, phlobatannin, triterpenoids, flavonoids, lipids, steroids, terpenoids, tannins and glycosides are identified in the extract by phytochemical screening. Leaf extract showed the presence of ethers and carboxylic acid groups (GCMS analysis). The leaf extract showed resistance against Salmonella typhi. Thus, from this study it can be concluded Clitoria ternatea leaves methanol extract has bioactive compounds showing anticancer activity against HL60 cells.Keywords
Antibacterial Activity, Anticancer Activity, Clitoria ternatea, GC-MS Analysis, Phytochemical Screening, MTT Assay.Full Text
References
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- Antimicrobial, Antioxidant and Anticancer Activity of the Ethanol Extract of Pleurotus ostreatus
Abstract Views :277 |
PDF Views:240
Authors
J. Bindhu
1,
Arunava Das
1,
E. Vihashinee
1,
A. Rubiga
1,
Aswin Edward
1,
R. Eswaran
1,
G. Shanmuga Priya
1,
S. Soundariya
1,
Aileen Rose Edwin
1
Affiliations
1 Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu, IN
1 Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu, IN
Source
Journal of Natural Remedies, Vol 20, No 2 (2020), Pagination: 110-115Abstract
The current study evaluates antimicrobial, antioxidant and anticancer activity of the ethanol extract of Pleurotus ostreatus. Chemical analysis showed the presence of alcohol, amides, alkanes, ether, phenol and sulphides. Most of the chemical constituents were found to be esters and carboxylic acid derivatives. The extract showed highest resistant against Bacillus cereus. P. ostreatus ethanol extract showed comparable antioxidant activity with ascorbic acid in both DPPH and FRAP method and also showed an IC50 of 39.29 μg/ml against HL60 cells.Keywords
MTT, DPPH, HL-60 Cells, FRAP, GC-MS.Full Text
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