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Wahi, A. K.
- Anti-diabetic Activity of Daemia extensa R. Br.
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Journal of Natural Remedies, Vol 2, No 1 (2002), Pagination: 80-83Abstract
Objective : The evaluation of antidiabetic activity of alcoholic and aqueous extracts of whole plant of Daemia extensa R Br. Materials and methods: The antidiabetic activity of both the extracts were evaluated using alloxan (120 mg/kg; i.p.) induced hyperglycemic rats. The potency of alcoholic and aqueous extracts were compared with that of reference drug chlopropamide. The blood glucose level was measured by using glucometer. Results: The alcoholic extract produced a highly significant fall in Blood Glucose Level (BGL) at 1 h after a single dose of the extract and in prolong treatment (i.e. for a week) the antidiabetic activity was maintained at par with the reference drug chlopropamide. Aqueous extract possess antidiabetic activity which was maintained upto 3 hours after a single dose and later the activity decreases but upon prolonged treatment, the peak activity was found on second day. Conclusion: Alcoholic extract of D. extensa is almost equipotent to chlorpropamide. This qualifies it to be used in ethnomedical diabetic management.Keywords
Daemia extensa, Anti-diabetic Activity, AlloxanFull Text
- Antidiabetic Activity of Barleria prionitis Linn.
Abstract Views :451 |
PDF Views:457
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Journal of Natural Remedies, Vol 1, No 1 (2001), Pagination: 64-66Abstract
Objective: To study antidiabetic effect of various parts of B. prionitis. Materials and methods: Antidiabetic activity of B. prionitis was evaluated using alloxan induced hyperglycemic rats. The potency of alcoholic and aqueous extracts of leaf, stem and ischolar_main was compared with that of chlorpropamide at a dose of 200 and 100mg/kg respectively. The blood glucose level was measured colorimetrically. Results: Alcoholic&aqueous extracts of leaf and ischolar_main caused significant fall in blood glucose level in diabetic rats. Conclusion: B. prionitis is almost equipotent to chlorpropamide in its ability to reduce the sugar levels and can be recommended for further studies.Keywords
Barleria Prionitis, Antidiabetic Activity, AlloxanFull Text