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Journal of Natural Remedies, Vol 12, No 1 (2012), Pagination: 68-71
Abstract
The ethanolic extract (D002) of the Phlebophyllum kunthianum (whole plant) was tested in vitro against Giardia lamblia and has been found to exhibit 100% antigiardial activity at the dose of 125 μg/ml. On bioassay guided fractionation of D002 by using the solvents of different polarity, n-butanol (F005) and aqueous fraction (F006) have been exhibited 100% antigiardial activity at the dose of 500 μg/ml and 250 μg/ml respectively. Fraction F011 prepared from F006 was found to be most active comparable to the D002 and exhibited 100% antigiardial activity at the dose of 125 μg/ml and number of live trophozoits of 13.48±0.97 at the MIC value of 62.5 μg/ml.
Keywords
Phlebophyllum kunthianum, Acanthaceae, Antigiardial Activity, Giardia lamblia
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