The PDF file you selected should load here if your Web browser has a PDF reader plug-in installed (for example, a recent version of Adobe Acrobat Reader).

If you would like more information about how to print, save, and work with PDFs, Highwire Press provides a helpful Frequently Asked Questions about PDFs.

Alternatively, you can download the PDF file directly to your computer, from where it can be opened using a PDF reader. To download the PDF, click the Download link above.

Fullscreen Fullscreen Off

Eremostachys laciniata (L.) Bunge (family: Lamiaceae) is one of the fifteen endemic Iranian herbs of the genus Eremostachys, and also grows in other central and western Asian countries. In the Iranian traditional medicine, this plant has been used as a local analgesic and as an anti-inflammatory remedy. In the present study, the methanol (MeOH) extract of the rhizomes of E. laciniata as well as the solid-phase extraction (SPE) fractions have been evaluated for their analgesic property in mice using the hot-plate test. All doses of the SPE 20% aq. MeOH fraction (P < 0.01) and the MeOH extract at the doses of 0.5 mg/kg (P < 0.01) and 1 mg/kg (P<0.05) displayed considerable analgesic effects. The analgesic effect of the SPE 20% aq. MeOH fraction (2.5 mg/kg) was more potent than that of the positive control, morphine (9 mg/kg) at 45 min after injection (P<0.001). However, SPE 40% aq. MeOH fraction did not show any analgesic effects at test doses.


Eremostachys Laciniata, Lamiaceae, Analgesic, Morphine, Mice, Hot-plate Test
Font Size