The PDF file you selected should load here if your Web browser has a PDF reader plug-in installed (for example, a recent version of Adobe Acrobat Reader).

If you would like more information about how to print, save, and work with PDFs, Highwire Press provides a helpful Frequently Asked Questions about PDFs.

Alternatively, you can download the PDF file directly to your computer, from where it can be opened using a PDF reader. To download the PDF, click the Download link above.

Fullscreen Fullscreen Off

The present study was undertaken to explore the effects of Cajanus indicus (Linn.) Mill. on airway inflammation and oxidative stress in ovalbumin-induced inflammation and antilipoxygenase activity in a murine model of asthma. The protective effect of extract of whole plant of Cajanus indicus (Linn.) Mill. against ovalbumin induced lung inflammation and arachidonic acid induced paw inflammation was evaluated. Hydroalcoholic extract of Cajanus indicus (Linn.) Mill.(CI) showed significant inhibition of total as well as differential leukocytes in the bronchalveolar lavage (BAL) fluid at dose of 350 and 525 mg/kg, p.o. (p<0.01).Pretreatment with CI significantly restored (p<0.01) the level of GSH, SOD,CATALASE and LPO in lungs. In BAL fluid, treatment of CI significantly reduced nitric oxide and total protein level. CI significantly inhibited arachidonic acid induced paw edema (p<0.01). Hence it can be concluded that Cajanus indicus (Linn.) Mill. has significant anti-inflammatory, antioxidant and antilipoxygenase effect.


Cajanus indicus, Asthma, Antioxidant, Ovalbumin
Font Size