The PDF file you selected should load here if your Web browser has a PDF reader plug-in installed (for example, a recent version of Adobe Acrobat Reader).

If you would like more information about how to print, save, and work with PDFs, Highwire Press provides a helpful Frequently Asked Questions about PDFs.

Alternatively, you can download the PDF file directly to your computer, from where it can be opened using a PDF reader. To download the PDF, click the Download link above.

Fullscreen Fullscreen Off


Objective: Develop a method to quantify a mixture of isoshinanolone and epi- isoshinanolone (ISMIX) as a specific marker for Plumbago indica L. in a commercial herbal drug, "Dasamoolarishtaya" (DMA). Materials and Methods: The ISMIX content in different DMA samples were analyzed by TLC fluorodensitometry. Isoshinanolone isolated from the root of P.indica was used as the standard. The precision and accuracy of the method were determined. Results: The concentrations of ISMIX in different samples of DMA varied widely from < 0.0012 mg/ml (detection limit of method) to 0.045 mg/ml. The precision was 1.52 % CV (n = 4) and recoveries of 99.2 - 100.8 % were obtained in standard addition recovery experiments. Conclusions: The method described is inexpensive, rapid and is of acceptable precision and accuracy for routine quality control work.

Keywords

Fluorodensitometry, Isoshinanolone, epi- Isoshinanolone, Quality Control, Standardization, Herbal Drugs
Font Size

User

Notifications
JOURNAL COVERS