Journal of Natural Remedies

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Objective: The present study is aimed to evaluate the leaf extracts of Abutilon indicum for acclaimed anti-diarrhoeal activity using albino rats. Materials and methods: Anti-diarrhoeal activity of Abutilon indicum was evaluated by gastro intestinal motility, castor oil-induced diarrhoea and prostaglandin E2 -induced enteropooling in rats. Loperamide was used as a standard drug. Results : The study revealed that, the methanolic extract and aqueous extract possessed significant antidiarrhoeal activity in castor oil-induced diarrhoea and prostaglandin E2-induced diarrhoea, compared to the control group. Conclusion: Abutilon indicum showed significant anti-diarrhoeal activity as compared to loperamide and can be recommended for further studies.

Keywords

Abutilon indicum, Loperamide, Antidiarrhoeal Activity, Albino Rats
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